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Carcinoma of the Nasopharynx

Abstract:

Nasopharyngeal carcinoma is as rare in Slovenia as in other Western countries. Given the etiopathogenetic interdependence of viral infection, neoplastic transformation and host immune response, nasopharyngeal carcinoma is a unique tumor model which can be studied from different perspectives. The complexity of nasopharyngeal anatomy and relationships of the nasopharynx to adjacent tissues has a decisive role in specifying treatment possibilities, expos­ing radiotherapy as a key treatment modality. The results of most recent retrospective and prospective randomized studies show that radiotherapy is successfully supplemented with chemotherapy. A routine use of new advances in technology, including computer tomogra­phy and magnetic resonance imaging, unified histology grading system and TNM staging system of the nasopharyngeal carcinoma, and improved treatment planning and execution of radiotherapy have yielded significantly better treatment results. Additional treatment of local, regional or systemic recurrences after completed initial treatment may be curative in a con­siderable proportion of patients.

Authors: Primož Strojan

Keywords: nasopharyngeal neoplasms, etiology, diagnosis, theraphy

Cite as: Med Razgl. 2004; 43: 385–402.


 
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