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The author reports a patient with acute liver and kidney failure diagnosed on his retur­ning from 14-day trip to Brasil, where he had been exposed to various risk factors for tropical di­seases. In spite of intensive care provided in an university medical institution, the patient died a few days after admission. The author discusses the differential diagnosis, stresses the role … Preberite več >>

The article presents some facts about vegetarian diet, its influence on child develop­ment, possible complications and their preven­tion. A vegetarian diet, if properly selected, can meet all the requirements of the growing child. A strictly vegetarian (vegan) diet can cause vi­tamin B₁₂ deficiency with serious neurological and haematological disturbances. To prevent vi­tamin B₁₂ deficiency we should recommend the … Preberite več >>

The supracondylar fractures of the hu­merus are the most common type of elbow fractures in children. They occur in either extension or fle­xion pattern. Both patterns have three types distin­guished by degree of displacement. This article deals with anatomy and embriology of the distal part of the humerus, reviews the symptoms, out­lines treatment principles and describes the general accepted methods … Preberite več >>

Patients with ovarian cancer are trea­ted individually. The basic method of treatment is the operation, precisely revealing the spread of disease and removing as much of the tumor as possible. Due to the nature of cancer spread, extensive and demanding operative procedures in the abdominal cavity are often necessary. Fol­lowing surgery, most patients are treated with cytostatics. Combinations of different … Preberite več >>

The advent of ultrasonography and computed tomography has facilitated the ima­ging of kidneys in patients with chronic renal fai­lure. Patients with diffuse renal parenchymal disease present with small, shrunken end-sta­ge kidneys, while those with autosomal-dominant polycystic kidney disease have very large kid­neys. Renal parenchyma echogenicity in patients treated with dialysis is increased compared to that in patients with normal renal … Preberite več >>

The recent technical development of echocardiography, especially transesophageal echocardiography, made the diagnosis of patent foramen ovale in adult life possible. The defect pre­disposes the patient to paradoxical embolism and is therefore of great clinical significance. There is a close association between patent foramen ova­le and ischemic stroke in both younger and older patients. Patent foramen ovale is found significantly more … Preberite več >>

Apoptosis, named as programmed cell death, represents one form of cell death and has a crucial role in the tissue homeostasis. Be­sides this, apoptosis is involved in a number of pathological conditions, such as cancer, auto-im­mune diseases and viral infections. Morphologi­cal characteristics of apoptosis are cell shrinkage, nuclear chromatin condensation and formation of apoptotic bodies. Apoptosis is genetically regu­lated process … Preberite več >>

Elevated plasma fibrinogen concen­tration is a risk factor for cardiovascular diseases. In addition to several factors such as advanced age, diabetes mellitus, cardiovascular disea­ses, elevated plasma cholesterol and glucose, and smoking, also genetic factors have been shown to influence plasma fibrinogen level. Stu­dies on influence of TaqI, HaeIII and BclI poly­morphisms on plasma fibrinogen concentration have shown … Preberite več >>