2017 » 2 »

BACKGROUNDS. Numerous scientific and clinical findings confirm that pain slows down the process of wound healing. In our previously published research, we presented a prototype of an analgesic wound dressing with two analgesics: lidocaine, a local anesthetic with immediate onset of effect for alleviation of pain caused by wound care, and diclofenac for further reduction of the pain present due … Preberite več >>

Anti-neutrophil cytoplasmic antibody vasculitis is a vasculitis of small vessels and can cause damage to many organs, most commonly the kidneys, upper and lower respiratory tract, gastrointestinal tract, skin, and nervous system. It is characterized by IgG antibodies that are directed against components of the cytoplasm of neutrophils. According to the immunofluorescence pattern, anti-neutrophil cytoplasmic antibodies are divided into antibodies … Preberite več >>

Haemostasis is a process in which a blood clot is formed in the wall of a damaged blood vessel. Haemostasis thus prevents blood loss while maintaining blood fluidity within the vascular system. The process includes a balanced cooperation of the elements of the vessel wall, blood platelets, and coagulation factors from blood plasma and damaged tissue cells. Haemostasis can be … Preberite več >>

Currently we do not yet know the populational burden of work-related and occupational neurological diseases. There is, however, scientific evidence for correlations between chemical, biological, and physical agents at workplace and different acute, subacute, and chronic neurological diseases and injuries. Exposure to pesticides and manganese is a risk factor for development of parkinsonism. Inhalation of diesel fumes, especially in professional … Preberite več >>

Familial hypercholesterolemia is a common genetic disorder. It is characterised by high cholesterol levels and early cardiovascular disease. With systematic biochemical testing in children, we can establish an early diagnosis of hypercholesterolemia. Furthermore, high risk individuals can be identified by measuring morphological and functional properties of arterial wall together with endothelial function assessment. In hypercholesterolemic children, early non-pharmacological (life-style change) … Preberite več >>

Prevalence and symptoms of musculoskeletal disorders increases with age due to repetitive load and degenerative changes. However, they are becoming more common even at a young age. In children, one of the ergonomic risk factors for developing pain is the use of school bag. The purpose of this literature review was to evaluate the scientific evidence on the possible association … Preberite več >>

The main role of parathyroid glands is regulation of calcium serum concentration by producing and secreting a peptide hormone named parathormone. Parathormone increases serum calcium level through the effects on bones, kidneys and intestines. Most common manifestation of parathyroid glands disorders is abnormal calcium level. Excessive secretion of parathormone causes hyperparathyroidism. We can distinguish between primary, secondary and tertiary hyperparathyroidism. … Preberite več >>

Fetal anemia is a potentially life-threatening condition in pregnancy that requires fast and accurate diagnosis, careful monitoring and appropriately timed action. Clinical presentation depends on several factors among which the most important are the etiology, rate of occurrence and the effectiveness of adaptive mechanisms to reduced tissue supply with oxygen. Through the case presentation, we would like to point out … Preberite več >>

The spine and the spinal cord receive blood from the network of arterial anastomoses, from the direct or indirect blood vessel connection of the spinal branching system. The anterior and posterior spinal arteries are the main blood vessels, which extend longitudinally along the anteromedial and posterolateral surface of the spinal cord. They are supplied with arterial blood by a number … Preberite več >>

The development of the spinal cord vascular system, vasculogenesis and later on angiogenesis, is influenced by various factors. The developmental process of arterial and venous system of the spinal cord begins in the fourth week. The spinal cord vascularization begins as a capillary network which is more numerous in the grey matter due to increased metabolic needs as in the … Preberite več >>

Adolescence is a very lively period, full of constant changes. In this period we frequently come across deliberate self-harm. In the management of adolescents who self-harm it is important to distinguish non-suicidal self-injurious behavior (NSSI) from suicidal behavior, because the former lacks suicidal intent. There are many risk factors that can attribute to NSSI, from age, sex, the social environment … Preberite več >>

A number of drugs have been withdrawn from the market or severely restricted in their use because of unexpected undesirable effects that became apparent only in the post market phase. In spite of the fact that these idiosyncratic drug reactions (IDR) are relatively rare (their incidence is 1 in 10,000–100,000 patients), they can be life-threatening and thus markedly increase the … Preberite več >>

BACKGROUND. Various types of hypothyroidism require different doses of levothyroxine in order to establish euthyroid state. However, previous studies frequently did not define the type of hypothyroidism and the factors influencing the adequacy of treatment. Therefore, the aim of the present study was to evaluate the treatment with levothyroxine in different well-defined types of hypothyroidism in greater detail. METHODS. In … Preberite več >>

BACKGROUNDS. Although head and neck cancers are not among the most frequent ones, they are important public health issue because of high mortality rates and their association with unhealthy lifestyle. In this paper, we present key epidemiological data, which represent the basis for efficient public health interventions. METHODS. We used incidence and mortality data for head and neck cancers (C00–C14, … Preberite več >>

Graves’ disease is an autoimmune thyroid disorder and the most frequent cause of hyperthyroidism in Slovenia. Antithyroid drugs are usually used as the first line of treatment. However, in rare cases they cause agranulocytosis with life-threatening neutropenia. We present a case of a patient who was simultaneously diagnosed to have Graves’ disease as well as moderate neutropenia, which was most … Preberite več >>

Tinea faciei is a superficial dermatophyte infection limited to the glabrous skin of the face. It is often seen in pediatric patients. Although the infective organisms and treatments are the same as for other superficial fungal infections, it is frequently misdiagnosed and modified or aggravated by administration of topical or systemic corticosteroids progressing to tinea incognito. We present a case … Preberite več >>