SI | EN

HOME
EDITORIAL BOARD
GUIDELINES FOR AUTHORS
CONTACT
LATEST EDITION
ARCHIVE
Anatomy
Anesthesiology
Biochemistry
Biophysics
Cell Biology
Clinical Cases
Dentistry
Dermatovenerology
Emergency Medicine
Family Medicine
Forensic Medicine
Gynecology and Obstetrics
Histology and Embryology
History of Medicine
Human Genetics
Hygiene
Infectious Diseases
Internal Medicine
Medical Deontology and Philosophy
Medical Psychology
Microbiology and Immunology
Neurology
Occupational Medicine
Oncology
Ophthalmology
Orthopaedics
Otorhinolaryngology
Pathology
Pathophysiology
Pediatrics
Pharmacology and Experimental Toxicology
Physical and Rehabilitation Medicine
Physiology
Psychiatry
Radiology
Social Medicine
Surgery
Toxicology
Research papers
Clinical research paper
Preclinical research paper
Sponsored articles

Metastatic Gastrinoma of the Liver

Abstract:

The gastrinoma was first described by the surgeons Zollinger and Ellison in 1955. The basic characteristics of this disease include an endocrine gastrin-secreting tumor of the gastrointestinal tract, gastric hypersecretion and recurrent gastric, duodenal and jejunal ulcers. The author reports on a 49-year-old female patient in whom a duodenal ulcer and two liver tumors, 10 and 6 cm in diameter, involving the right and the left lobe, respectively, were diagnosed in 1982. A liver biopsy specimen, obtained during explorative laparotomy, was defined histologically as a metastatic small-cell ephitelial tumor with an organoid endocrine pattern. Its morphological pattern was that of a tumor of APUD series. A gatrinoma was verified by immunohistochemical staining. Serum gastrin levels exceeded the normal range by 10 times. The patient refused any further treatment. In the following years, she received several conservative treatments for sequelae of her ulcer disease. For the past three years she has been treated on an out-patient basis, mostly for chronic diarrhea.

Authors: Skok Pavel

Keywords: Zollinger-Ellison syndrome, gastrinoma, secondary liver neoplasms

Cite as: Med Razgl. 1997; 36: 109–16.


 
Društvo Medicinski razgledi
Korytkova ulica 2
1000 Ljubljana
E [email protected]
T (01) 524 23 56
F (01) 543 70 11


Working hours:
MON 7 AM - 8 AM
TUE 7 AM - 8 AM
WED no office hours
THU 7 AM - 8 AM
FRI no office hours

IBAN SI56 0201 4005 0652 588
VAT N° SI64004643
Reg. N° 1203401
Facebook
Twitter
LinkedIn
Google+
Supporters