{"id":1258,"date":"2013-08-17T14:35:55","date_gmt":"2013-08-17T14:35:55","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=1258"},"modified":"2013-08-18T12:13:31","modified_gmt":"2013-08-18T12:13:31","slug":"carotid-intima-media-thickness-in-young-patients-with-familial-hypercholesterolemia","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/carotid-intima-media-thickness-in-young-patients-with-familial-hypercholesterolemia\/","title":{"rendered":"Carotid Intima-Media Thickness in Young Patients with Familial Hypercholesterolemia"},"content":{"rendered":"<p>Familial hypercholesterolemia, an inheritable metabolic disorder, is the most pow\u00aderful risk factor for the accelerated atheroscle\u00adrosis. Mean intima-media thickness of carotid arteries was determined with B-mode ultra\u00adsonography in 28 young patients with familial hypercholesterolemia and in 28 normolipemic subjects. Serum lipids, lipoprotein(a), glucose, coagulation and fibrinolytic parameters were determined. Mean intima-media thickness was significantly greater in patients with familial hyper\u00adcholesterolemia than in controls (0.71\u00b10.15 vs. 0.49\u00b10.08 mm, p&lt;0.0001). In all subjects together mean intima-media thickness was pos\u00aditively correlated with total cholesterol, low-density lipoprotein cholesterol, triglycerides, and systolic blood pressure. In patients with famil\u00adial hypercholesterolemia mean intima-media thickness was positively correlated with age and systolic blood pressure, while in controls it was correlated with systolic blood pressure, body weight and height, triglycerides and tissue plasminogen activator antigen and it was greater in males than females. Multiple regression analy\u00adsis identified the group of patients with familial hypercholesterolemia, higher triglycerides and age as the independent determinants of IMT in all subjects together, while in controls these determinants were sex, age and triglyceride level.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Familial hypercholesterolemia, an inheritable metabolic disorder, is the most pow\u00aderful risk factor for the accelerated atheroscle\u00adrosis. Mean intima-media thickness of carotid arteries was determined with B-mode ultra\u00adsonography in 28 young patients with familial hypercholesterolemia and in 28 normolipemic subjects. Serum lipids, lipoprotein(a), glucose, coagulation and fibrinolytic parameters were determined. Mean intima-media thickness was significantly greater [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[284],"tags":[],"class_list":["post-1258","post","type-post","status-publish","format-standard","hentry","category-latest"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Carotid Intima-Media Thickness in Young Patients with Familial Hypercholesterolemia - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/debelina-intime-in-medije-karotidnih-arterij-pri-mladostnikih-z-druzinsko-hiperholesterolemijo\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Carotid Intima-Media Thickness in Young Patients with Familial Hypercholesterolemia - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Familial hypercholesterolemia, an inheritable metabolic disorder, is the most pow\u00aderful risk factor for the accelerated atheroscle\u00adrosis. Mean intima-media thickness of carotid arteries was determined with B-mode ultra\u00adsonography in 28 young patients with familial hypercholesterolemia and in 28 normolipemic subjects. Serum lipids, lipoprotein(a), glucose, coagulation and fibrinolytic parameters were determined. 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