{"id":1865,"date":"2013-08-19T16:33:30","date_gmt":"2013-08-19T16:33:30","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=1865"},"modified":"2013-08-19T16:33:30","modified_gmt":"2013-08-19T16:33:30","slug":"effects-of-epigenetic-modifications-on-male-gamete-development-and-function","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/effects-of-epigenetic-modifications-on-male-gamete-development-and-function\/","title":{"rendered":"Effects of Epigenetic Modifications on Male Gamete Development and Function"},"content":{"rendered":"<div>\n<p>Epigenetic DNA modifications participate in genome regulation. These marks modulate the gene expression pattern and, on the whole genome scale, provide a cell-specific expression profile. They are pivotal to development, as they first enable preimplantation embryo pluripotency and, later on, cell differentiation. Because these marks are dynamic, they allow for the development of germ cell. In this review, DNA methylation, histone modifications and RNA interference are presented and their possible role in male germ cell development is discussed. Some early evidence linking erroneous epigenetic marks to male gamete (spermatozoon) dys\u00adfunction is also presented.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Epigenetic DNA modifications participate in genome regulation. These marks modulate the gene expression pattern and, on the whole genome scale, provide a cell-specific expression profile. They are pivotal to development, as they first enable preimplantation embryo pluripotency and, later on, cell differentiation. Because these marks are dynamic, they allow for the development of germ cell. [&hellip;]<\/p>\n","protected":false},"author":30,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[284],"tags":[],"class_list":["post-1865","post","type-post","status-publish","format-standard","hentry","category-latest"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Effects of Epigenetic Modifications on Male Gamete Development and Function - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/vpliv-epigenetskih-modifikacij-na-razvoj-in-funkcijo-moske-gamete\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Effects of Epigenetic Modifications on Male Gamete Development and Function - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Epigenetic DNA modifications participate in genome regulation. These marks modulate the gene expression pattern and, on the whole genome scale, provide a cell-specific expression profile. They are pivotal to development, as they first enable preimplantation embryo pluripotency and, later on, cell differentiation. Because these marks are dynamic, they allow for the development of germ cell. 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