{"id":1884,"date":"2013-08-19T16:43:10","date_gmt":"2013-08-19T16:43:10","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=1884"},"modified":"2013-08-19T16:43:10","modified_gmt":"2013-08-19T16:43:10","slug":"new-knowledge-of-renin-angiotensin-aldosterone-system-and-new-strategies-of-its-blockade","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/new-knowledge-of-renin-angiotensin-aldosterone-system-and-new-strategies-of-its-blockade\/","title":{"rendered":"New Knowledge of Renin-Angiotensin-Aldosterone System and New Strategies of its Blockade"},"content":{"rendered":"<div>\n<p>The renin-angiotensin-aldosterone system is a hormone system that is vital for the regula\u00adtion of arterial blood pressure, electrolyte balance and extracellular fluid volume in the body. Since the discovery of renin in 1898 and later the renin-angiotensin-aldosterone system, there have been numerous studies on its effects and influences on physiological and pathophysiological mechanisms in different organs. The classical renin-angiotensin-aldosterone system pathway that begins with the release of renin from the kidneys, through angiotensin-I, angiotensin-II and aldosterone formation is a widely known concept that could now be described as incom\u00adplete. There is increasing evidence of the existence of a tissue renin-angiotensin-aldosterone system but it has been unsatisfactorily blocked with the blocking strategies known to date. The objective of this paper is to address new knowledge about the renin-angiotensin-aldosterone system and new strategies for its blockage.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The renin-angiotensin-aldosterone system is a hormone system that is vital for the regula\u00adtion of arterial blood pressure, electrolyte balance and extracellular fluid volume in the body. Since the discovery of renin in 1898 and later the renin-angiotensin-aldosterone system, there have been numerous studies on its effects and influences on physiological and pathophysiological mechanisms in different [&hellip;]<\/p>\n","protected":false},"author":30,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[382,420],"tags":[],"class_list":["post-1884","post","type-post","status-publish","format-standard","hentry","category-4-2008-archive","category-physiology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New Knowledge of Renin-Angiotensin-Aldosterone System and New Strategies of its Blockade - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Knowledge of Renin-Angiotensin-Aldosterone System and New Strategies of its Blockade - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"The renin-angiotensin-aldosterone system is a hormone system that is vital for the regula\u00adtion of arterial blood pressure, electrolyte balance and extracellular fluid volume in the body. Since the discovery of renin in 1898 and later the renin-angiotensin-aldosterone system, there have been numerous studies on its effects and influences on physiological and pathophysiological mechanisms in different [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\/\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2013-08-19T16:43:10+00:00\" \/>\n<meta name=\"author\" content=\"\u010crt Zavrnik\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u010crt Zavrnik\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/\"},\"author\":{\"name\":\"\u010crt Zavrnik\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/80418a5a6b59976483b5d19fc87a9092\"},\"headline\":\"New Knowledge of Renin-Angiotensin-Aldosterone System and New Strategies of its Blockade\",\"datePublished\":\"2013-08-19T16:43:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/\"},\"wordCount\":146,\"commentCount\":0,\"articleSection\":[\"4\",\"Physiology\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/nova-spoznanja-o-reninsko-angiotenzinsko-aldosteronskem-sistemu-in-nove-strategije-njegove-zavore\\\/\",\"name\":\"New Knowledge of Renin-Angiotensin-Aldosterone System and New Strategies of its Blockade - 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