{"id":2807,"date":"2013-08-27T13:53:53","date_gmt":"2013-08-27T13:53:53","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=2807"},"modified":"2013-08-27T14:25:30","modified_gmt":"2013-08-27T14:25:30","slug":"a-study-of-cutaneous-reactive-hyperaemia-by-laser-doppler-flowmeter","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/a-study-of-cutaneous-reactive-hyperaemia-by-laser-doppler-flowmeter\/","title":{"rendered":"A study of cutaneous reactive hyperaemia by laser-Doppler flowmeter"},"content":{"rendered":"<p>Finger nailfold skin blood flow was monitored by laser-Doppler flowmeter in 18\u2028 healthy volunteers after the occlusion of digital\u2028arteries. The primary aim of the study was to characterize the microcirculatory pattern of \u2028postocclusive reactive hyperaemia. Laser-Doppler flowmetry revealed two parts of the hyperaemic response. The first part was characterized by maximum laser-Doppler flow and\u2028 large amplitude of the oscillations which correspond to heart beats. The second part was \u2028characterized by the appearance of periodic \u2028oscillation with fundamental frequency from\u2028 0.07 to 0.19 Hz. In order to elucidate the physiological background of this phenomenon, the \u2028cutaneous vascular bed was exposed to the changes of transmural pressure, secured by different position of the limb, and to different levels of ischaemia, accomplished by varying the duration of occlusion. It was found that the\u2028 area under the first part of laser-Doppler flow increased with prolongation of arterial occlusion. The increment was found to be significant between 1 and 4 (p=0.009) and 4 and 8\u2028 (p=0.006) minutes of occlusion. Also, the area\u2028 proved to be independent of transmural pressure (R=0.06, p=0.74). In contrast, the fundamental frequency of periodic oscillations in the\u2028 second part of the response proved to be pressure dependent but showed no significant correlation with the duration of arterial occlusion \u2028(p&lt;0.001). It is our conclusion that the first part\u2028 of laser-Doppler hyperaemic response reflects\u2028 predominant contribution of metabolic components in contrast to the periodic oscillations in\u2028 the second part of the response, which very likely reflect myogenic response.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Finger nailfold skin blood flow was monitored by laser-Doppler flowmeter in 18\u2028 healthy volunteers after the occlusion of digital\u2028arteries. The primary aim of the study was to characterize the microcirculatory pattern of \u2028postocclusive reactive hyperaemia. Laser-Doppler flowmetry revealed two parts of the hyperaemic response. The first part was characterized by maximum laser-Doppler flow and\u2028 large [&hellip;]<\/p>\n","protected":false},"author":25,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[306,420],"tags":[],"class_list":["post-2807","post","type-post","status-publish","format-standard","hentry","category-2-1993-archive","category-physiology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A study of cutaneous reactive hyperaemia by laser-Doppler flowmeter - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A study of cutaneous reactive hyperaemia by laser-Doppler flowmeter - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Finger nailfold skin blood flow was monitored by laser-Doppler flowmeter in 18\u2028 healthy volunteers after the occlusion of digital\u2028arteries. The primary aim of the study was to characterize the microcirculatory pattern of \u2028postocclusive reactive hyperaemia. Laser-Doppler flowmetry revealed two parts of the hyperaemic response. The first part was characterized by maximum laser-Doppler flow and\u2028 large [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\/\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2013-08-27T13:53:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2013-08-27T14:25:30+00:00\" \/>\n<meta name=\"author\" content=\"Miha Ora\u017eem\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Miha Ora\u017eem\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/\"},\"author\":{\"name\":\"Miha Ora\u017eem\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/39b3f838f2cf9572ee7ba4e165cf307b\"},\"headline\":\"A study of cutaneous reactive hyperaemia by laser-Doppler flowmeter\",\"datePublished\":\"2013-08-27T13:53:53+00:00\",\"dateModified\":\"2013-08-27T14:25:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/\"},\"wordCount\":249,\"commentCount\":0,\"articleSection\":[\"2\",\"Physiology\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/studij-kozne-reaktivne-hiperemije-z-laser-dopplerskim-tokomerom\\\/\",\"name\":\"A study of cutaneous reactive hyperaemia by laser-Doppler flowmeter - 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