{"id":3164,"date":"2013-09-03T21:03:54","date_gmt":"2013-09-03T21:03:54","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=3164"},"modified":"2013-09-06T23:38:37","modified_gmt":"2013-09-06T23:38:37","slug":"dermatologic-manifestations-of-the-hypereosinophilic-syndrome","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/dermatologic-manifestations-of-the-hypereosinophilic-syndrome\/","title":{"rendered":"Dermatologic Manifestations of the Hypereosinophilic Syndrome"},"content":{"rendered":"<p>Hypereosinophilic syndrome represents a range of rare and heterogeneous disorders shar\u00ading three features: peripheral eosinophil count higher than 1.5 x 10<sup>9<\/sup>\/L for over 6 months, evi\u00addence of organ involvement and absence of other causes of eosinophilia, such as allergy, parasite infestation and malignancy. Hypereosinophilic syndrome may present with various cutaneous abnormalities. Over 50% of such patients have pruritic erythematous macules, papules, plaques, wheals, nodules, or other skin lesions during the course of the disease. The diagnosis of hyper\u00adeosinophilic syndrome may be delayed or missed because the association between cutaneous lesions and hypereosinophilic syndrome is not appreciated. The presence of eosinophils in normal tissues is surprisingly selective. Eosinophil infiltration or degranulation is not seen in skin samples from normal persons. The treatment goal for patients with hypereosinophilic syndrome is to provide relief of symptoms and improvement in organ function while keep\u00ading eosinophils in peripheral blood at 1000-2000\/mL and minimizing side effects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hypereosinophilic syndrome represents a range of rare and heterogeneous disorders shar\u00ading three features: peripheral eosinophil count higher than 1.5 x 109\/L for over 6 months, evi\u00addence of organ involvement and absence of other causes of eosinophilia, such as allergy, parasite infestation and malignancy. Hypereosinophilic syndrome may present with various cutaneous abnormalities. Over 50% of such [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[385,416],"tags":[],"class_list":["post-3164","post","type-post","status-publish","format-standard","hentry","category-3-2009-archive","category-dermatovenerology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dermatologic Manifestations of the Hypereosinophilic Syndrome - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/dermatoloske-manifestacije-hipereozinofilnega-sindroma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dermatologic Manifestations of the Hypereosinophilic Syndrome - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Hypereosinophilic syndrome represents a range of rare and heterogeneous disorders shar\u00ading three features: peripheral eosinophil count higher than 1.5 x 109\/L for over 6 months, evi\u00addence of organ involvement and absence of other causes of eosinophilia, such as allergy, parasite infestation and malignancy. Hypereosinophilic syndrome may present with various cutaneous abnormalities. 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