{"id":5860,"date":"2013-09-16T06:37:30","date_gmt":"2013-09-16T06:37:30","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=5860"},"modified":"2013-09-16T06:37:30","modified_gmt":"2013-09-16T06:37:30","slug":"clinical-experience-with-high-doses-of-atorvastatin","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/clinical-experience-with-high-doses-of-atorvastatin\/","title":{"rendered":"Clinical experience with high doses of atorvastatin"},"content":{"rendered":"

Cardiovascular diseases (CVDs) represent an important healthcare problem in Europe. Among\u00a0the objectives of cardiovascular disease prevention a more rigorous risk factor control is needed, including control of cholesterol levels. In clinical practice, reaching the target lipid values\u00a0may be difficult which could be easier achievable by using high doses of statins. Therefore\u00a0we conducted a study with atorvastatin 40mg (Atoris, Krka, d.d., Novo mesto) on 787 high-risk
\npatients with hyperlipidemia. Atorvastatin 40 mg produced a statistically significant relative reduction in the total cholesterol level (by 28,5%), LDL cholesterol level (by 34,7%), and\u00a0triglyceride level (by 21,5%). In the group of patients without previous treatment with a hypolipidemic agent, a mean reduction in the total cholesterol level by 31,9% and a mean reduction\u00a0in the LDL cholesterol level by 37,7% were observed. The tolerability of atorvastatin 40 mg\u00a0was excellent, as adverse reactions related to drug occurred in only 3% of the patients. After\u00a0completing the study, 97% of all patients continued therapy with 40 mg or even 80 mg of atorvvastatin daily.<\/p>\n","protected":false},"excerpt":{"rendered":"

Cardiovascular diseases (CVDs) represent an important healthcare problem in Europe. Among\u00a0the objectives of cardiovascular disease prevention a more rigorous risk factor control is needed, including control of cholesterol levels. In clinical practice, reaching the target lipid values\u00a0may be difficult which could be easier achievable by using high doses of statins. Therefore\u00a0we conducted a study with […]<\/p>\n","protected":false},"author":28,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[377,406],"tags":[],"class_list":["post-5860","post","type-post","status-publish","format-standard","hentry","category-4-2007-archive","category-sponsored-articles"],"acf":[],"yoast_head":"\nClinical experience with high doses of atorvastatin - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/?p=5786\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical experience with high doses of atorvastatin - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Cardiovascular diseases (CVDs) represent an important healthcare problem in Europe. Among\u00a0the objectives of cardiovascular disease prevention a more rigorous risk factor control is needed, including control of cholesterol levels. In clinical practice, reaching the target lipid values\u00a0may be difficult which could be easier achievable by using high doses of statins. Therefore\u00a0we conducted a study with […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/?p=5786\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2013-09-16T06:37:30+00:00\" \/>\n<meta name=\"author\" content=\"Sara Mugerli\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sara Mugerli\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786\"},\"author\":{\"name\":\"Sara Mugerli\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/16ac1255597e2446044919a9c6902c99\"},\"headline\":\"Clinical experience with high doses of atorvastatin\",\"datePublished\":\"2013-09-16T06:37:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786\"},\"wordCount\":169,\"commentCount\":0,\"articleSection\":[\"4\",\"Sponsored articles\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/?p=5786#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786\",\"name\":\"Clinical experience with high doses of atorvastatin - Dru\u0161tvo Medicinski razgledi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\"},\"datePublished\":\"2013-09-16T06:37:30+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/16ac1255597e2446044919a9c6902c99\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/?p=5786\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/?p=5786#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Clinical experience with high doses of atorvastatin\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/\",\"name\":\"Dru\u0161tvo Medicinski razgledi\",\"description\":\"Dru\u0161tvo Medicinski razgledi\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/medrazgl.si\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/16ac1255597e2446044919a9c6902c99\",\"name\":\"Sara Mugerli\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2986e968b4413be533684bfc019b504b946f9a82220511cb4bcf7a3428a735dd?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2986e968b4413be533684bfc019b504b946f9a82220511cb4bcf7a3428a735dd?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2986e968b4413be533684bfc019b504b946f9a82220511cb4bcf7a3428a735dd?s=96&d=mm&r=g\",\"caption\":\"Sara Mugerli\"},\"url\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/author\\\/sara-mugerli\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Clinical experience with high doses of atorvastatin - Dru\u0161tvo Medicinski razgledi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medrazgl.si\/?p=5786","og_locale":"en_US","og_type":"article","og_title":"Clinical experience with high doses of atorvastatin - Dru\u0161tvo Medicinski razgledi","og_description":"Cardiovascular diseases (CVDs) represent an important healthcare problem in Europe. 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