{"id":5884,"date":"2013-09-16T09:16:16","date_gmt":"2013-09-16T09:16:16","guid":{"rendered":"http:\/\/test-medrazgl.aed-baza.si\/?p=5884"},"modified":"2013-09-16T09:16:16","modified_gmt":"2013-09-16T09:16:16","slug":"the-influence-of-different-doses-of-subcutaneously-transplanted-ehrlich-ascites-tumor-cells-on-the-development-of-the-tumor","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/the-influence-of-different-doses-of-subcutaneously-transplanted-ehrlich-ascites-tumor-cells-on-the-development-of-the-tumor\/","title":{"rendered":"The influence of different doses of subcutaneously transplanted Ehrlich ascites tumor cells on the development of the tumor"},"content":{"rendered":"<p>The authors transplanted Ehrlich ascites tumor (EAT) cells to 90 inbred mice of CBA strain in order to investigate the role that sex of animal and dose of tumor cells plau in the development and growth of the subcutaneous tumor, and to evaluate histologically the metastatic rate. They transplanted\u00a013,6 x 10^6, 13,6 x 10^4, and 13,6 x 10^2 tumor cells, respectively, to three groups of animals. With the first two doses, transplantation succeeded in 100% of cases, while with the last it was successful n 13,3% of males and 40% of females. The dose of transplanted tumor cells was found to be inversely proportional to survival, and proportional to the subcutaneous tumor growth. With the same dose of transplanted tumor cells, a significantly shorter survival and a smaller tumor bulk were observed in females as compared to males. Histological examination of all viscera except the brain showed the highest metastatic rate in the lung, kidney, suprarenal glands and pararenal lymph nodes. It was not influenced by the tumor dose or sex of the animal.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The authors transplanted Ehrlich ascites tumor (EAT) cells to 90 inbred mice of CBA strain in order to investigate the role that sex of animal and dose of tumor cells plau in the development and growth of the subcutaneous tumor, and to evaluate histologically the metastatic rate. They transplanted\u00a013,6 x 10^6, 13,6 x 10^4, and [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[300,440,408],"tags":[],"class_list":["post-5884","post","type-post","status-publish","format-standard","hentry","category-1-1992-archive","category-pathology","category-preclinical-research-paper"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The influence of different doses of subcutaneously transplanted Ehrlich ascites tumor cells on the development of the tumor - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/vpliv-razlicnega-stevila-podkozno-presajenih-celic-ehrlichovega-ascitesnega-tumorja-na-razvoj-tumorja\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The influence of different doses of subcutaneously transplanted Ehrlich ascites tumor cells on the development of the tumor - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"The authors transplanted Ehrlich ascites tumor (EAT) cells to 90 inbred mice of CBA strain in order to investigate the role that sex of animal and dose of tumor cells plau in the development and growth of the subcutaneous tumor, and to evaluate histologically the metastatic rate. 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