{"id":7462,"date":"2014-05-31T14:42:32","date_gmt":"2014-05-31T12:42:32","guid":{"rendered":"http:\/\/medrazgl.si\/?p=7462"},"modified":"2014-06-02T00:43:10","modified_gmt":"2014-06-01T22:43:10","slug":"post-authorization-safety-and-efficacy-study-of-escitalopram-ecytara-in-the-treatment-of-depression-and-anxiety-disorders","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/post-authorization-safety-and-efficacy-study-of-escitalopram-ecytara-in-the-treatment-of-depression-and-anxiety-disorders\/","title":{"rendered":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders"},"content":{"rendered":"<div title=\"Page 100\">\n<div>\n<div>\n<p>BACKGROUNDS. Depression is the most common mental disorder and is a serious mental illness. It is a mental disorder that pose a real problem to the public health care system. Early diagnosis and treatment is instrumental in a relatively good management and control of disease. Selective serotonin reuptake inhibitors are first-line drugs for depression treatment according to guidelines. METHODS. We conducted a post-authorisation study in which 389 patients with depression and anxiety disorders received escitalopram (Ecytara\u00ae). After eight weeks of treatment (average dose of 11.6 mg), 296 patients were included in the analysis of the effectiveness. RESULTS. The symptom expression was reduced in 98 % of patients. Due to symptom improvement, 63 % of patients became only marginally ill or symptom-free. Escitalopram was well tolerated by patients. During monitoring, medicine-related adverse reactions were noted in 10.7 % of patients, while at the end of monitoring the number fell to 1.1 %. The post-authorisation study showed that the most frequent adverse reaction was nausea with frequency of 4.1 %. CONCLUSIONS. Escitalopram is efficient and safe antidepressant and is suitable for depression and anxiety disorder treatment.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>BACKGROUNDS. Depression is the most common mental disorder and is a serious mental illness. It is a mental disorder that pose a real problem to the public health care system. Early diagnosis and treatment is instrumental in a relatively good management and control of disease. Selective serotonin reuptake inhibitors are first-line drugs for depression treatment [&hellip;]<\/p>\n","protected":false},"author":43,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[399,418,442,406],"tags":[],"class_list":["post-7462","post","type-post","status-publish","format-standard","hentry","category-2-2012-archive","category-pharmacology-and-experimental-toxicology","category-psychiatry","category-sponsored-articles"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"BACKGROUNDS. Depression is the most common mental disorder and is a serious mental illness. It is a mental disorder that pose a real problem to the public health care system. Early diagnosis and treatment is instrumental in a relatively good management and control of disease. Selective serotonin reuptake inhibitors are first-line drugs for depression treatment [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2014-05-31T12:42:32+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2014-06-01T22:43:10+00:00\" \/>\n<meta name=\"author\" content=\"Valentina Ahac\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Valentina Ahac\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/\"},\"author\":{\"name\":\"Valentina Ahac\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/afd0f3231ee7ab8b2ed1e4aeed3eefeb\"},\"headline\":\"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders\",\"datePublished\":\"2014-05-31T12:42:32+00:00\",\"dateModified\":\"2014-06-01T22:43:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/\"},\"wordCount\":187,\"commentCount\":0,\"articleSection\":[\"2\",\"Pharmacology and Experimental Toxicology\",\"Psychiatry\",\"Sponsored articles\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/\",\"name\":\"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\"},\"datePublished\":\"2014-05-31T12:42:32+00:00\",\"dateModified\":\"2014-06-01T22:43:10+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/afd0f3231ee7ab8b2ed1e4aeed3eefeb\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/\",\"name\":\"Dru\u0161tvo Medicinski razgledi\",\"description\":\"Dru\u0161tvo Medicinski razgledi\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/medrazgl.si\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/afd0f3231ee7ab8b2ed1e4aeed3eefeb\",\"name\":\"Valentina Ahac\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g\",\"caption\":\"Valentina Ahac\"},\"url\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/author\\\/valentina-ahac\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/","og_locale":"en_US","og_type":"article","og_title":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi","og_description":"BACKGROUNDS. Depression is the most common mental disorder and is a serious mental illness. It is a mental disorder that pose a real problem to the public health care system. Early diagnosis and treatment is instrumental in a relatively good management and control of disease. Selective serotonin reuptake inhibitors are first-line drugs for depression treatment [&hellip;]","og_url":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/","og_site_name":"Dru\u0161tvo Medicinski razgledi","article_published_time":"2014-05-31T12:42:32+00:00","article_modified_time":"2014-06-01T22:43:10+00:00","author":"Valentina Ahac","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Valentina Ahac","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/#article","isPartOf":{"@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/"},"author":{"name":"Valentina Ahac","@id":"https:\/\/medrazgl.si\/#\/schema\/person\/afd0f3231ee7ab8b2ed1e4aeed3eefeb"},"headline":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders","datePublished":"2014-05-31T12:42:32+00:00","dateModified":"2014-06-01T22:43:10+00:00","mainEntityOfPage":{"@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/"},"wordCount":187,"commentCount":0,"articleSection":["2","Pharmacology and Experimental Toxicology","Psychiatry","Sponsored articles"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/","url":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/","name":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders - Dru\u0161tvo Medicinski razgledi","isPartOf":{"@id":"https:\/\/medrazgl.si\/#website"},"datePublished":"2014-05-31T12:42:32+00:00","dateModified":"2014-06-01T22:43:10+00:00","author":{"@id":"https:\/\/medrazgl.si\/#\/schema\/person\/afd0f3231ee7ab8b2ed1e4aeed3eefeb"},"breadcrumb":{"@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/medrazgl.si\/neintervencijsko-spremljanje-varnosti-in-ucinkovitosti-escitaloprama-ecytara-v-zdravljenju-depresije-in-anksioznih-motenj\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/medrazgl.si\/en\/"},{"@type":"ListItem","position":2,"name":"Post-Authorization Safety and Efficacy Study of Escitalopram (Ecytara\u00ae) in the Treatment of Depression and Anxiety Disorders"}]},{"@type":"WebSite","@id":"https:\/\/medrazgl.si\/#website","url":"https:\/\/medrazgl.si\/","name":"Dru\u0161tvo Medicinski razgledi","description":"Dru\u0161tvo Medicinski razgledi","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medrazgl.si\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/medrazgl.si\/#\/schema\/person\/afd0f3231ee7ab8b2ed1e4aeed3eefeb","name":"Valentina Ahac","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c5057f6dbe272a0fc7eaa25ec10f809b38127c54b939c4deecc793fc9184f850?s=96&d=mm&r=g","caption":"Valentina Ahac"},"url":"https:\/\/medrazgl.si\/en\/author\/valentina-ahac\/"}]}},"_links":{"self":[{"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/posts\/7462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/comments?post=7462"}],"version-history":[{"count":0,"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/posts\/7462\/revisions"}],"wp:attachment":[{"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/media?parent=7462"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/categories?post=7462"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medrazgl.si\/en\/wp-json\/wp\/v2\/tags?post=7462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}