{"id":8421,"date":"2014-06-03T10:48:17","date_gmt":"2014-06-03T08:48:17","guid":{"rendered":"http:\/\/medrazgl.si\/?p=8421"},"modified":"2014-06-03T10:48:17","modified_gmt":"2014-06-03T08:48:17","slug":"chediak-higashi-syndrome","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/chediak-higashi-syndrome\/","title":{"rendered":"Che\u0301diak-Higashi Syndrome"},"content":{"rendered":"<div title=\"Page 90\">\n<div>\n<div>\n<p>Che\u0301diak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. It is a rare autosomal recessive disorder. The treatment consists of bone marrow transplantation, which corrects the immunologic and hematologic defects. Nevertheless, oculocutaneous and neurological changes persist. Untreated patients die as the result of bacterial infections or develop \u00bbaccelerated phase\u00ab lymphoproliferation.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Che\u0301diak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. It is a rare autosomal recessive disorder. The treatment consists of bone marrow transplantation, which corrects the immunologic and hematologic defects. Nevertheless, oculocutaneous and neurological changes persist. Untreated patients die as the result of bacterial infections or [&hellip;]<\/p>\n","protected":false},"author":35,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[682,424,426],"tags":[],"class_list":["post-8421","post","type-post","status-publish","format-standard","hentry","category-2-2013-archive","category-human-genetics","category-internal-medicine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Che\u0301diak-Higashi Syndrome - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/chediak-higashijev-sindrom\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Che\u0301diak-Higashi Syndrome - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Che\u0301diak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. It is a rare autosomal recessive disorder. The treatment consists of bone marrow transplantation, which corrects the immunologic and hematologic defects. Nevertheless, oculocutaneous and neurological changes persist. Untreated patients die as the result of bacterial infections or [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/chediak-higashijev-sindrom\/\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2014-06-03T08:48:17+00:00\" \/>\n<meta name=\"author\" content=\"Matej Gori\u010dar\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Matej Gori\u010dar\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/\"},\"author\":{\"name\":\"Matej Gori\u010dar\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\"},\"headline\":\"Che\u0301diak-Higashi Syndrome\",\"datePublished\":\"2014-06-03T08:48:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/\"},\"wordCount\":63,\"commentCount\":0,\"articleSection\":[\"2\",\"Human Genetics\",\"Internal Medicine\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/\",\"name\":\"Che\u0301diak-Higashi Syndrome - Dru\u0161tvo Medicinski razgledi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\"},\"datePublished\":\"2014-06-03T08:48:17+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/chediak-higashijev-sindrom\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Che\u0301diak-Higashi Syndrome\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/\",\"name\":\"Dru\u0161tvo Medicinski razgledi\",\"description\":\"Dru\u0161tvo Medicinski razgledi\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/medrazgl.si\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\",\"name\":\"Matej Gori\u010dar\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"caption\":\"Matej Gori\u010dar\"},\"url\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/author\\\/matej-goricar\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Che\u0301diak-Higashi Syndrome - Dru\u0161tvo Medicinski razgledi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medrazgl.si\/chediak-higashijev-sindrom\/","og_locale":"en_US","og_type":"article","og_title":"Che\u0301diak-Higashi Syndrome - Dru\u0161tvo Medicinski razgledi","og_description":"Che\u0301diak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. 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