{"id":8518,"date":"2014-06-04T10:55:46","date_gmt":"2014-06-04T08:55:46","guid":{"rendered":"http:\/\/medrazgl.si\/?p=8518"},"modified":"2014-06-04T10:55:46","modified_gmt":"2014-06-04T08:55:46","slug":"severe-death-cap-poisoning","status":"publish","type":"post","link":"https:\/\/medrazgl.si\/en\/severe-death-cap-poisoning\/","title":{"rendered":"Severe Death Cap Poisoning"},"content":{"rendered":"<div title=\"Page 82\">\n<div>\n<div>\n<p>Death cap (lat. <em>Amanita phalloides<\/em>) is generally considered the most toxic known mushroom. Amatoxins (the main toxin being \u03b1-amanitin), which death cap produces, are the most toxic cyclopeptides. They cause liver, renal and central nervous system damage. Within the cell they bind to the RNA-polymerase II and inhibit DNA transcription. The result is the arrest of cell&#8217;s protein synthesis. The three-phase clinical course is characteristic: the first phase consists of gastrointestinal toxicity, the second is represented by transient improvement and the third one is characterized by late onset hepatic failure and renal failure. The case report represents a 30-year-old female with severe death cap poisoning. \u03b1-amanitin caused acute hepatic failure and related complications, which almost required liver transplantation. With the help of intensive treatment we avoided the need for transplantation and enabled the patient&#8217;s full recovery.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Death cap (lat. Amanita phalloides) is generally considered the most toxic known mushroom. Amatoxins (the main toxin being \u03b1-amanitin), which death cap produces, are the most toxic cyclopeptides. They cause liver, renal and central nervous system damage. Within the cell they bind to the RNA-polymerase II and inhibit DNA transcription. The result is the arrest [&hellip;]<\/p>\n","protected":false},"author":35,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[684,428,446],"tags":[],"class_list":["post-8518","post","type-post","status-publish","format-standard","hentry","category-4-2013-archive","category-clinical-cases","category-toxicology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Severe Death Cap Poisoning - Dru\u0161tvo Medicinski razgledi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medrazgl.si\/huda-zastrupitev-z-zeleno-musnico\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Severe Death Cap Poisoning - Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"og:description\" content=\"Death cap (lat. Amanita phalloides) is generally considered the most toxic known mushroom. Amatoxins (the main toxin being \u03b1-amanitin), which death cap produces, are the most toxic cyclopeptides. They cause liver, renal and central nervous system damage. Within the cell they bind to the RNA-polymerase II and inhibit DNA transcription. The result is the arrest [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medrazgl.si\/huda-zastrupitev-z-zeleno-musnico\/\" \/>\n<meta property=\"og:site_name\" content=\"Dru\u0161tvo Medicinski razgledi\" \/>\n<meta property=\"article:published_time\" content=\"2014-06-04T08:55:46+00:00\" \/>\n<meta name=\"author\" content=\"Matej Gori\u010dar\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Matej Gori\u010dar\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/\"},\"author\":{\"name\":\"Matej Gori\u010dar\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\"},\"headline\":\"Severe Death Cap Poisoning\",\"datePublished\":\"2014-06-04T08:55:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/\"},\"wordCount\":142,\"commentCount\":0,\"articleSection\":[\"4\",\"Clinical Cases\",\"Toxicology\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/\",\"name\":\"Severe Death Cap Poisoning - Dru\u0161tvo Medicinski razgledi\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\"},\"datePublished\":\"2014-06-04T08:55:46+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/huda-zastrupitev-z-zeleno-musnico\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Severe Death Cap Poisoning\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#website\",\"url\":\"https:\\\/\\\/medrazgl.si\\\/\",\"name\":\"Dru\u0161tvo Medicinski razgledi\",\"description\":\"Dru\u0161tvo Medicinski razgledi\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/medrazgl.si\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/medrazgl.si\\\/#\\\/schema\\\/person\\\/34d7ecbf2c9ebf96d826c5634daed7ca\",\"name\":\"Matej Gori\u010dar\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/003f8c4b027e5f6651eec48509adb56770581509ef227519d254087e28cffac3?s=96&d=mm&r=g\",\"caption\":\"Matej Gori\u010dar\"},\"url\":\"https:\\\/\\\/medrazgl.si\\\/en\\\/author\\\/matej-goricar\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Severe Death Cap Poisoning - Dru\u0161tvo Medicinski razgledi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medrazgl.si\/huda-zastrupitev-z-zeleno-musnico\/","og_locale":"en_US","og_type":"article","og_title":"Severe Death Cap Poisoning - Dru\u0161tvo Medicinski razgledi","og_description":"Death cap (lat. 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