2024 »

Chronic limb-threatening ischemia (CLTI) is a clinical diagnosis with objectively confirmed
atherosclerotic peripheral arterial disease, leading to varying degrees of ischemia
and presenting as ischemic rest pain and/or tissue loss, such as ulceration or gangrene.
Hemodynamic parameters usually associated with CLTI are an ankle-brachial index < 0.4,
absolute ankle perfusion pressure <50mmHg, toe pressure <30mmHg, or transcutaneous
oximetry < 30mmHg. … Preberite več >>

Superficial venous thrombosis (SVT) is an inflammation of the venous wall with subsequent
secondary thrombus formation. In the majority of cases, it affects the superficial
venous system of the lower extremities. SVT which appears in functionally and structurally
normal veins without varicose changes is a heterogeneous group of diseases in which
different etiopathogenetic mechanisms are present with varying expressions of … Preberite več >>

Pulmonary embolism (PE) represents a major cause of cardiovascular morbidity and mortality.
Over the last few years, there has been an increase in the incidence of PE, while
simultaneously the mortality rates associated with PE have been declining. The improved
survival rates in PE are likely to result from the better availability of more precise diagnostic
methods, better adherence to … Preberite več >>

BACKGROUNDS. In favourable anatomical conditions, endovascular abdominal aneurysm
repair (EVAR) or thoracic endovascular aortic repair (TEVAR) are the established treatments
of aortic aneurysms. The treatment of other areas is more complex and demands
more complex endovascular procedures or open surgery. Multilayer flow modulators (MFM)
were developed to treat aortic aneurysms in areas where standard EVAR or TEVAR are
not feasible. … Preberite več >>

The use of a serial high-sensitivity troponin assays enables the diagnosis of a peri-operative
myocardial infarction/injury (PMI), which proved to be a valuable peri-operative
prognostic marker. An absolute increase of post-operative high-sensitivity cardiac troponin
T or I in more than the upper limit of normal above the pre-operative concentration
was associated with an important increase in 30-day and long-term mortality … Preberite več >>

Hormonal-induced changes in haemostasis, fibrinolysis, blood flow, and the vessel wall
are the reasons why venous thromboembolisms are more common in pregnancy than
in non-pregnant women of the same age. The clinical presentation of venous thromboembolisms
is more unreliable than in non-pregnant women; an objective diagnosis should
be performed in suspected cases, and some peculiarities related to pregnancy should be… Preberite več >>

Despite progress in primary and secondary prevention, atherosclerotic cardiovascular
disease remains one of the leading causes of mortality. Long-term exposure to elevated
levels of low-density lipoprotein (LDL) cholesterol is a significant risk factor for its
development. Various treatment strategies for hypercholesterolemia exist; however, their
success is limited. Treatment with tested and registered humanized monoclonal antibodies
against proprotein convertase subtilisin/kexin type … Preberite več >>

Native aortic valve thrombosis is an exceptionally rare and serious condition characterized
by the formation of a thrombus on the native aortic valve. It presents a significant clinical
challenge and can lead to severe complications, including heart failure or cardiogenic
shock due to a heart attack or aortic valve dysfunction, neurological issues such as stroke,
and peripheral embolisms affecting the … Preberite več >>

Venous thromboembolism often occurs in patients with cancer. The risk of venous thromboembolism
is increased because of the prothrombotic state (platelet activation, increased
tissue factor expression) as well as cancer treatment (surgery, central venous lines,
chemotherapy). On the other hand, thrombocytopenia also frequently develops in cancer
patients due to cancer itself (e.g., in haematological malignancies) or due to anti-cancer
therapy. … Preberite več >>

BACKGROUNDS. Myocardial perfusion imaging (MPI) is a well-established non-invasive
imaging technique for the diagnosis of coronary artery disease (CAD). MPI may detect
obstructive CAD but fail to discover subclinical atherosclerosis. With advances in technology,
low-dose CT for attenuation correction has become an important part of nuclear
cardiology. CT in MPI allows for the visualization of thoracic aorta calcification (TAC)
and … Preberite več >>

Surgical treatment of septic endarteritis of the iliofemoral region can result in prolonged
ischemia of the lower extremities. Distal perfusion of the limb can improve early postoperative
outcomes. We present a case of a 35-year-old woman who was diagnosed with
septic endarteritis of the right iliofemoral region as a consequence of residual wire fragments
from a prior endovascular procedure. During … Preberite več >>

BACKGROUNDS. The aim of this pilot study was to determine the benefits of hyperbaric
oxygen (HBO) therapy for chronic wounds in patients with chronic limb-threatening ischemia
(CLTI). METHODS. The study was performed as a retrospective cohort study, with five
patients with CLTI included. Patients were treated with HBO after endovascular treatment
(EVT). Treatment sessions involved daily exposure to high oxygen … Preberite več >>

BACKGROUNDS. Endovascular abdominal aortic aneurysm repair (EVAR) is commonly
used to treat abdominal aortic aneurysms (AAA). In our department, the outcomes
following EVAR after 30 days, one year and later have been monitored systematically
in all patients since 2023. METHODS. All the patients after EVAR, which were hospitalized
at our department from January 2023 until May 2024, have been included … Preberite več >>