Caring for Chronic Limb-Threatening Ischemia Patients Undergoing Vascular Interventions

Chronic limb-threatening ischemia (CLTI) is a clinical diagnosis with objectively confirmed
atherosclerotic peripheral arterial disease, leading to varying degrees of ischemia
and presenting as ischemic rest pain and/or tissue loss, such as ulceration or gangrene.
Hemodynamic parameters usually associated with CLTI are an ankle-brachial index < 0.4,
absolute ankle perfusion pressure <50mmHg, toe pressure <30mmHg, or transcutaneous
oximetry < 30mmHg. The following article will cover the topics of CLTI prognosis and
risk factor treatment as well as the approach to revascularisation procedures with periprocedural
or postprocedural treatment especially regarding antithrombotic regimens to
improve vessel patency.