This article presents the Alzheimer’s Disease Assessment Scale-Cognitive (ADAS-Cog) for the measurement of disease progression and the patient’s response to drug treatment for Alzheimer’s disease. Previous scales had only limited utility because of low sensitivity and restrict­ed scope. The ADAS-Cog provides more com­prehensive and detailed information, meets practical standards and is easy to administer. Special training, however, is needed for adminis­tering the test. The scale is designed to measure all the major symtpoms of dementia and determine the increase in the symptom severity; the test is reliable and suitable for the use in a variety of set­tings. It comprises 11 cognitive items, including spo­ken language ability, comprehension of spoken language, recall of test instructions, word-finding problems in spontaneous speech, following com­mands, naming objects and fingers, construc­tional and ideational praxis, orientation, word-recall and word-recognition tasks. Despite the above mentioned advantages ADAS-Cog cannot replace an extensive neuropsychological test.