Chédiak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. It is a rare autosomal recessive disorder. The treatment consists of bone…

Fertilization is the process of paternal and maternal chromosomes uniting in the activated oocyte. The most frequent reason for fertilization failure is sperm incapacity to penetrate into the oocyte. In…

Elevated plasma fibrinogen concen­tration is a risk factor for cardiovascular diseases. In addition to several factors such as advanced age, diabetes mellitus, cardiovascular disea­ses, elevated plasma cholesterol and glucose, and…

Two polymorphic sites of the CYP1A1 gene, coding for cytochrome P4501A1 enzyme, have been discovered so far. One involves the 7th exon of the coding region; a nucleotide chan­ge leads…