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Extensive technological advancements in imaging scanners and material equipment lead to the more important role of percutaneous procedures on the musculoskeletal system, which became more precise, safer and more efficient during the past decade. The aim of percutaneous diagnostic procedures is to etiologically define skeletal or soft tissue lesions. The most important percutaneous diagnostic procedure is percutaneous bone or soft … Preberite več >>

Hepatocellular carcinoma is the most common primary liver malignancy. Imaging modalities for detection and follow-up include ultrasound, contrast enhanced ultrasound, computed tomography and magnetic resonance imaging. Early detection of the hepatocellular carcinoma enables better treatment options for the patient. The prognosis and treatment planning is determined according to the Barcelona Clinic Liver Cancer classification. Early stage of the disease is … Preberite več >>

Portal vein embolization is an interventional radiologic procedure used in the preoperative treatment of patients scheduled for major hepatic resection. The procedure induces hypertrophy of the non-diseased portion of liver and thereby reduces the possibility of postoperative liver failure. In this article, we present a case of a 50-year old patient
with preoperative portal vein embolization before right hepatectomy for … Preberite več >>

Percutaneous transthoracic needle biopsy and transthoracic radiofrequency ablation are interventional procedures, which represent an important alternative to more invasive surgical approaches in the diagnosis and treatment of pulmonary lesions. One of the most common imaging modalities for guidance of both transthoracic procedures is computed tomography. The selection of the appropriate needle as well as intervention planning primarily depends on the … Preberite več >>

BACKGROUNDS. Although head and neck cancers are not among the most frequent ones, they are important public health issue because of high mortality rates and their association with unhealthy lifestyle. In this paper, we present key epidemiological data, which represent the basis for efficient public health interventions. METHODS. We used incidence and mortality data for head and neck cancers (C00–C14, … Preberite več >>

Neuroendocrine tumors of the stomach are rare tumors representing less than 2% of polypoid lesions of the stomach. They are frequently discovered incidentally on endoscopic examination, but they can also cause symptomatic anemia or abdominal pain. Gastric neuroendocrine tumors are derived from enterochromaffin-like cells and they have a known
malignant potential. Usually they are multiple and associated with multiple endocrine … Preberite več >>

Head and neck cancer accounts for approximately  5 % of all cancers, which makes it the sixth most common form of cancerin terms of its frequency of occurence. In Slovenia approximately 450 people are diagnosed with this cancer every year. The most common head and neck cancer site of metastasis are lymph nodes in the neck, which account for 40 … Preberite več >>

Bone metastases are significantly more common than primary neoplasms. Solid tumors, which spread to the bone most frequently, originate from the breast, prostate, thyroid gland or kidney cancer. These metastases can be divided into complicated and simple, whilst their structure can be osteolytic, osteoblastic or mixed. The clinical manifestations found in patients with bone metastases can present themselves as bone … Preberite več >>

Malignant spinal cord compression can lead to permanent neurological dysfunction and is therefore considered an oncological emergency. It is mostly caused by metastases to the spinal column, most frequently from breast, prostate and lung cancer, multiple myeloma and lymphoma. Clinically, it presents with pain, muscle weakness and autonomic dysfunction. The diagnostic method of choice is magnetic resonance imaging or computed … Preberite več >>

Cancer patients today live longer and have a better quality of life. This is mainly due to a multidisciplinary approach in cancer diagnostics. A close collaboration between pathologists, who perform histopathological examination and molecular or genetic typization, is nowadays crucial for a proper treatment. These disciplines allow us to identify targets in cancer cells and direct targeted therapy directly to … Preberite več >>

BACKGROUNDS. Type 2 diabetes mellitus (DM) and breast cancer are common diseases in the developed world which share certain risk factors. There are several possible pathophysiological mechanisms which could explain increased incidence of breast cancer in patients with type 2 DM, including increased circulating insulin level. Because certain types of treatment for type 2 DM are associated with increased circulating … Preberite več >>

Malignant melanoma is an unpredictable, aggressive disease with the fastest growing incidence among all cancers. Its high metastatic potential and tendency to relapse are poorly prevented by existing systemic therapy. In spite of apparent eradication through treatment in accordance with the newest clinical guidelines, the disease is likely to recur. Cancer stem cells, with their plasticity, self-renewal ability and drug … Preberite več >>

Urinary incontinence is a common side effect of treatment of gynecological cancers and has an important negative effect on the patients’ quality of life. It can be caused by all of the three main treatment methods in gynecological oncology, namely by surgical procedures, radia­tion and chemotherapy. Urinary incontinence can result from the treatment of all kinds of gynecological cancers; its … Preberite več >>

Keratoacanthoma is an epidermal malignancy, which histopathologically resembles to squamous cell carcinoma. Multiple keratoacanthomas are a heterogeneous group of inherited or acquired disorders. Several different mechanisms may be responsible for their development, including UV radiation, ionizing radiation, viruses (human papillomavirus), and chemical carcinogens (tar), as well as certain immunologic and genetic factors. The article is a report on three patients … Preberite več >>