Oncology
Preventive Effects of Natural Antioxidants on Ultraviolet − Induced Skin Cancer
The incidence of non-melanoma skin cancer is rising and primary prevention, including the use of sunscreens, has been proven inadequate. Skin cancer strongly correlates with chronic sun exposure. Here we…
Read more ›Frequency of BRCA1 and BRCA2 Gene Mutations in Slovenian Male Breast Cancer Patients
Breast cancer is the most frequent cancer among women in Slovenia. Male breast cancer, however, is a rare disease comprising less than 1% of breast cancer patients in Slovenia. The…
Read more ›Fluidity of Red Blood Cells’ Membranes in Cancer Patients − an Electronic Paramagnetic Resonance Study
Background: Hypocholesterolemia in cancer patients is a frequent and expected phenomenon. Higher fluidity of plasma membranes (as a result of lower concentration of cholesterol) is a characteristic of most cancer…
Read more ›Pulmonary Metastasis
Metastatic malignant neoplasms are the most common form of secondary lung tumors. These are neoplastic lesions originating at a site that is distinct from the primary lesion. Due to the…
Read more ›The role of specific and non-specific immune mechanisms in defence against tumors
In the article are described some key mechanisms, used by an immune system to distinguish a tumor cell from a normal, healthy cell. According to bulk of the literature in…
Read more ›Early gastric cancer – comparison of endoscopic stage evaluation, definitive histological stage assessment, treatmant and survival rate
Clinical diagnosis of early gastric cancer was established in 51 of 262 patients with gastric cancer. The aim of the study was to determine the accuracy of clinical diagnosis, and…
Read more ›Human Telomere and Telomerase: Structure, Function and Role in Cancerogenesis
With each somatic cell division, the chromosomal ends, or telomeres, progressively shorten. Critically shortened telomeres are recognised by DNA repair systems as DNA damage, the cells are withdrawn from the…
Read more ›Prognostic factors in ovarian cancer
In ovarian cancer the recognition of the prognostic factors allows an accurate planning of treatment, monitoring of patients and evaluation of the course of disease. Some factors depend only on the characteristics of the…
Read more ›Identification of genes alterations in stomach cancer
Stomach cancer (gastric adenocacinoma) is a common malignant disease in Slovenia. The Lauren's classification distinguishes between a well differentiated intestinal type and a poorly differentiated diffuse type of the disease, which differ in…
Read more ›Inoperable Carcinoma of the Head and Neck: Contemporary Treatment
Contemporary management and treatment of most malignant diseases are conducted in multidisciplinary teams. New knowledge in the field of tumor biology and about molecular mechanisms related to function of chemotherapeutics,…
Read more ›Prognostic Factors in Breast Cancer
The factors used in planning breast cancer treatment and predicting the course of disease at the present level of scientific development are presented. The most significant independent prognostic factor is…
Read more ›Breast Cancer: the Characteristics and Detection Methods
Breast cancer is the most frequent malignant disease in women. It is alarming that in most countries and including Slovenia the number of women afflicted by and dying of this…
Read more ›Immunotherapy of Tumors
Immune interventions were introduced in the treatment of human cancer about 100 years ago. Thanks to the development of monoclonal antibodies and molecular gene technology during the past 15 years,…
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