Since 1962.

Toxicology

Fluphenazine Poisoning – Case Report

Antipsychotics are a heterogeneous group of drugs with multiple usages. Poisoning with antipsychotics is the eight most common poisoning with drugs affecting the neural system. Due to a high number…
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Severe Death Cap Poisoning

Death cap (lat. Amanita phalloides) is generally considered the most toxic known mushroom. Amatoxins (the main toxin being α-amanitin), which death cap produces, are the most toxic cyclopeptides. They cause…
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Acetaminophen Intoxication – Case Report

We present a case of acute acetaminophen intoxication, which is a commonly used analgesic and antipyretic drug. It can be bought over the counter, which makes it widely available. Fast…
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Ethylene Glycol Intoxication

Ethylene glycol intoxications are quite rare. The toxicity of ethylene glycol is largely related to its metabolites rather than the parent compound itself. Our case report represents the typi­cal clinical…
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Cocaine Induced Acute Renal Failure

Acute renal failure is characterised by a rapid decline in glomerular filtration rate over hours 341 to days. Causes of acute renal failure are varied and include cocaine abuse. Cocaine…
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Medicinal Mushrooms: from Historical Preparations to Modern Science

In the past medicinal mushrooms have been widely used in Asia, but over the past several years dietary supplements containing medicinal mushrooms have also been introduced on the pharmaceutical and food market…
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Poisoning by Chemical Warfare Agents

Chemical warfare agents are defined as any chemical substance whose toxic properties are utilized to kill, injure or incapacitate an enemy in warfare and associated military operations. There has been a legislative…
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Amphetamine and Methamphetamine: Mechanism of Action, Effects, Poisoning and Diagnostics

Amphetamine consumption is highly spread throughout the world, especially in the Unites States of America, Australia and Asia. In Slovenia, the consumption of amphetamines and methamphetamines is not so spread and, further…
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Bites by Venomous Snakes

Eight different species of non-venomous snakes of the Colubridae family, and three different species of poisonous snakes of the Viperidae family are native in Slovenia. In the period bet­ween 1999…
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Mushroom Poisoning

There are about 200 different types of edible mushrooms and some 50 types of more or less poisonous mushrooms in Slovenia. Depending on the toxin and clinical presentation, mush­room poisoning…
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Diagnostics and Treatment of Organic Solvents Poisoning

Organic solvents are a heterogeneous group of chemicals with different chemical structures which are usually used in the form of mixtures. They often contain toxic impurities or addi­tives. Their toxicity…
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Toxicokinetics and Toxicodynamics of Organic Solvents

Organic solvents are a class of liquid organic chemicals called hydrocarbons. Their common properties are volatility and lipophilicity. These characteristics make inhalation the major route of solvent exposure and provide…
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Diagnostics and Treatment of Metals Poisonings

Knowledge about the toxicokinetics and toxicodynamics of various types and forms of each metal is very important for the diagnostics and assessment of the seriousness of poisoning and for the…
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Toxicology of (Heavy) Metals

Metals differ from other toxic substances in that they are not destroyed in nature. Furthermore, they may be transported over great distances and they have a tendency toward accumula­tion in…
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Intoxication with Pesticides

Pesticides are agents intended for killing, preventing, repelling or mitigating any pest. They continue to be used extensively despite limiting regulations in many countries. Their wide­spread use and availability have…
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Gas Poisoning

5.5% of all intoxications occur as a consequence of inhaling a toxic substance (gases, fumes, vapours or aerosols), in particular asphyxiant and irritant gases. Gases are absorbed through the lungs…
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Poisoning with Antiepileptic Drugs

Antiepileptic drugs are used for the treatment and prevention of epileptic attacks, chronic pain syndrome, bipolar disorder, and migraine. Although they are quite a heterogeneous group of medicines, they have…
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Antidotes

Antidotes are medicinal products that neutralize, inactivate, adsorb, counteract or by whichev­er way decrease toxic effects of poisons. Regarding their action they are divided into physi­cal, chemical or physiologic antidotes.…
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Decontamination and Elimination of Poisons

In addition to symptomatic and supportive treatment, decontamination of the digestive tract is frequently the only therapeutic measure in the case of poison ingestion. Decontamination of the skin and eyes…
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Diagnostics and Treatment in Acute Poisoning

In addition to well known toxic plants and animals, rapid development in the last decades has produced millions of new molecules, toxic chemicals, drugs and potentially toxic pro­ducts, which can…
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