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There are about 200 different types of edible mushrooms and some 50 types of more or less poisonous mushrooms in Slovenia. Depending on the toxin and clinical presentation, mush­room poisoning is classified into various syndromes. This article presents a review of the mush­room groups causing individual poisoning syndromes and the pharmacodynamics and pharmacokinetics of the toxins, as well as the clinical presentation and treatment of the syn­dromes. The amatoxin, orelanine, muscarin, ibotenic, coprine, gyromitrin, gastrointestinal and psilocybin syndromes are described.