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The care and therapy of the skin, which is mechanically, postoperativelly or per­manently converted, is based on the primary dermatotherapeutical principles. The contempo­rary adjustment of therapeutic substances to the skin changes and use of hydrocolloid skin bar­riers provides prevention and therapy of the chronic skin injury. Suitable therapeutic sub­stances offer natural skin protection, accerelate healing and make patient feeling more com­fortable and safe.