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Chronic exertional compartment syndrome can occur in all body parts in which compartments can be found. Most frequently, it emerges in the lower leg (95%) in athletes, in whom running represents the greatest strain. The diagnosis consists of the patient’s history, clinical status, radiological procedures and pressure measurements in connective tissues within the damaged compartment. When pressure exceeds normal values, fasciotomy is required. This article contains the descriptions of clinical characteristics in cases with affected lower leg, as well as their diagnostics and therapy.