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Essential arterial hypertension is one of the commonest chronic diseases of circulation system. Before the onset of raised blood pressure, the functional and morphological changes of the left ventricle develop. The aim of the study was to asses functional and possible morphological characteristics of left ventricle with concomitant biochemical parameters in young normotensive individuals with familial trait of hypertension. We searched for relationships between functional and biochemical parameters and evaluated eventual independent correlations between them. This cross-sectional study included 76 subjects, 44 in study and 32 in control group. We performed clinical examination and took blood for biochemical analysis. Using classical echocar- diographical technique and tissue pulse Doppler echocardiography, we estimated morphological characteristics and diastolic function of the heart. There were differences between study and control group in anthropometric indexes and blood pressure, as well as in some biochemical parameters. Classic echocardiographical investigation revealed changes in morphology and diastolic function of left ventricle. Tissue Doppler echocardiography confirmed differences in relaxation (Em/Am ratio: 1,19 ± 0,35 vs 1,67 ± 0,33, p< 0,001; two-tailed Student’s t-test) and compliance (E/Em: 7,51 ±1,28 vs 6,60±1,02, p = 0,001; two-tailed Student’s t-test) of left ventricle. The groups did not differ in systolic function. In all subjects, relaxation parameters of left ventricle were negatively correlated with positive family history, male gender, higher anthropometric indexes, blood pressure and insulin concentrations (r = -0,58, p < 0,001; Spearman’s correlation). Multiple regression model analysis revealed independent influence of positive family history, male gender and insulin concentration on relaxation properties (R2 = 0,51; p< 0,001). We also established correlations between changes in diastolic function and left ventricular mass and enlarged left atrium, on the other hand, there was no correlation with aldosterone concentrations. Study groups differed in parameters, which are a constitutive part of metabolic syndrome. It seems that functional changes of left ventricle are not dependent upon blood pressure; they may even be inherited. The aldosterone concentration was not correlated with diastolic function of left ventricle.