The article presents the recommendations for immunization of children with chronic kid­ney disease of higher stages and children with idiopathic nephrotic syndrome. These chil­dren are in some cases more susceptible to serious viral and bacterial infections. The prevention of infectious diseases by efficacious vaccination is very important in these children there­fore they should receive all recommended standard vaccines for healthy children whenever it is possible and there are also some additional vaccinations recommended. It should be empha­sized that live attenuated vaccines should be avoided in children after renal transplantation and in children with idiopathic nephrotic syndrome on immunosuppressive therapy.