MENU
Anatomy
Anesthesiology
Biochemistry
Biomedical Informatics
Biophysics
Cell Biology
Clinical Cases
Dentistry
Dermatovenerology
Emergency Medicine
Family Medicine
Forensic Medicine
Gynecology and Obstetrics
Histology and Embryology
History of Medicine
Human Genetics
Hygiene
Infectious Diseases
Internal Medicine
Medical Deontology and Philosophy
Medical Psychology
Microbiology and Immunology
Neurology
Occupational Medicine
Oncology
Ophthalmology
Orthopaedics
Otorhinolaryngology
Pathology
Pathophysiology
Pediatrics
Pharmacology and Experimental Toxicology
Physical and Rehabilitation Medicine
Physiology
Psychiatry
Radiology
Social Medicine
Surgery
Toxicology
Research papers
Clinical research paper
Preclinical research paper
Sponsored articles
Archive » 2010 » 2 » | Archive » Medical field » Fields » Biophysics » Archive » Medical field » Fields » Cell Biology »

Microvesicles from Blood Plasma Observed by Electron Microscopy

 
Abstract:

This post is also available in: enEnglish slSlovenščina (Slovenian)

Lateral redistribution of molecules in cell membrane may result in budding and shedding of vesicles smaller than micrometer, called microvesicles. Microvesicles reflect in their cha­racteristics the state and type of cells wherefrom they originate. The state of cells may be changed in diseases therefore also microvesicles, which originate from those cells, characte­ristically represent the disease and are an interesting potential diagnostic tool. Despite nume­rous studies and publications there is still no standard protocol for microvesicle isolation and characterisation from the peripheral blood. In this work we used electron microscopy as a pos­sible tool for characterisation of microvesicles and for determination of possible artefacts acqui­red in the isolation procedure. Scanning electron microscopy proved useful for determination of three-dimensional form of microvesicles. Transmission electron microscopy enabled the insight into inner structure of microvesicles.

Authors:
Šuštar Vid, Frank Mojca, Janša Vid, et al.

Keywords:
microvesicles, electron microscopy, blood plasma, ultrastructure

Cite as:
Med Razgl. 2010; 49: 137–44.

Download PDF >>
© 2021 Društvo Medicinski razgledi | Na vrh strani / To top ↑