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The demand for outpatient surgery and office-case anesthesia is increasing for medical, technological and economic reasons. Ophtalmic day-case surgery and anesthesia have developed over the past ten years. Careful selection of ambulatory patients, preoperative evaluation, good control of the symptoms of pre-existing diseases which is in the hands of the patient’s personal physician and internist and optimal intra- and post operative anesthesiological management reduce the perioperative risks associated with the patient’s pre-existing chronic diseases. Prevention of postoperative nausea and vomiting and good postoperative analgesia make home care for such patients easy and comfortable, and reduce the incidence of complications. High-quality and cost-effective outpatient ophtalmic surgery and anesthesia require close cooperation between the surgeon, the anesthesiologist and the patient’s general practitioner.