Santorio Santorio (1561−1636), a physician born in Capodistria, introduced new worth into medicine with his quantitative approach. The possibility of numeric monitoring and measuring various physiological and pathological processes within the human body, i. e. metabolism or recording of body temperature, brought exactness in expression into medicine, along with the possibility of proving results. Santorio was Galileo’s pupil and accepted his mechanistic principles, introducing them in his work De medicina statica. His work influenced many generations of physicians. This article mainly discusses Santorio’s influence on Baglivi, a physician from Dubrovnik.