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The dose of hormones in nwe low-dose hormonal contraceptive pills is ten times lower than in the first contraceptives used in early sixties. Adverse side-effects which for the most part depend on the dose of hormones have thus been markedly reduced. Positive effects are based on the suppression of ovulation, therefore hormonal contraceptives have a very favourable benefit/risk ratio. In addition to the established oral hormonal contraceptive method, new routes of administration and new steroids with antihormonal effect have been gaining ground. Currently, clinical trials of some non-steroid hormones, as GnRH.analogues, are underway.