Since 1962.

Histamine Receptor Type 3 – from Gene to Drug Target

Histamine receptor type 3 was discovered in 1983 by Schwartz and coworkers and cloned in 1999. The expression of histamine receptor type 3 is largely confined to the central nervous…
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Chédiak-Higashi Syndrome

Chédiak-Higashi syndrome is characterized by varying degrees of oculocutaneous albinism, recurrent infections, bleeding disorders and variable neurological involvement. It is a rare autosomal recessive disorder. The treatment consists of bone…
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Diabetes Mellitus Type 1 and Subcutaneous Continuous Insulin Infusion (Insulin Pump) Therapy in Children and Adolescents

Diabetes is a common endocrine disorder. According to the data from the World Health Organization and the International Diabetes Federation, almost 250 million people are suffering from diabetes around the…
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Differential Diagnosis of Back Pain in Children and Adolescents

Epidemiological studies have shown that about 50% of children younger than 15 years have already experienced low back pain. In most cases, this can be attributed to either wearing overweight…
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Cognitive Impairment after Ischemic Stroke

Stroke is the primary cause of morbidity and disability throughout the world, mainly because of its effect on cognitive functions. After stroke, individuals can recover from physical disability, but might…
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Anatomy of Four Liver Systems and Liver Division into Functional Units

Functional anatomy of the liver is based on three-dimensional arrangement of four liver systems – portal, arterial, biliary and the system of hepatic veins. On the basis of the intrahepatic…
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Testing of Warm/Cold Sensation as an Additional Procedure in the Diabetic Foot Screening Test

BACKGROUNDS. Early detection of patients who are at risk for the development of a foot ulcer is crucial in the prevention of diabetic gangrene. The pathophysiology of diabetic foot ulceration…
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