This post is also available in: English Slovenščina (Slovenian)

We studied 44 patients receiving venom immunotherapy. Among the patients who suffered insect sting during the immunotherapy period, the number of subjects responding only by local reaction (60%) or mild sistemic problems increased with the duration of immunotherapy. As concerns side effects of hiposenzibilization, they occurred much more frequently in women than in men. Also, atopic subjects were more likely to develop severe systemic reactions to insect sting than non-atopic individuals. We discovered that after three years of immunotherapy the specific IgE/IgG index changed significantly, while no statistically significant difference occurred in specific IgE and IgG serum concentrations. As indicated by the results of our investigation, the degree of insect sting toleration can be more accurately evaluated by determining the specific IgE/IgG index than by specific IgE or IgG measurements.