Since 1962.

1994

Life-threatening infections in childhood

Life-threatening infections rarely occur in children, but when they do they require immediate diagnosis and therapy. The principal aetiologic agents are bacteria and viruses, other microorganisms being less common. The…
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New aspects about hepatitis A

The paper describes new views on hepatitis A, a new classification of hepatitis A virus, its epidemiology, clinical picture, treatment and prevention, passive immunization and recently introduced active immunization with…
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Dependence diseases

The author presents some recent views on the disorders due to psychoactive substances use and groups them according to the Diagnostic and Statistical Manual of Mental Disorders Classification. He explains…
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Echocardiography of the right heart

The paper deals with the right heart, an issue rarely discussed in the cardiologic literature. Despite the avaible imaging techniques, evaluation of the right heart and the right ventricle in…
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The effect of lipoprotein(a) on fibrinolysis in vitro

Lipoprotein(a) is an independent risk factor for atherosclerotic disease. Because of its structural similarity to plasminogen, lipoprotein(a) in high concentrations may inhibit fibrinolysis, thus promoting the development of atherosclerosis. Since…
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The influence of nicardipin and its enantiomers on enteral absorption of digoxin in guinea pig in vivo

Simultaneous administration of digoxin and calcium channel blockers results in increased plasma levels of digoxin. One of the possible mechanisms of this interaction could be a changed enteral absorption of…
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Immunotherapy of Tumors

Immune interventions were introduced in the treatment of human cancer about 100 years ago. Thanks to the development of mon­oclonal antibodies and molecular gene tech­nology during the past 15 years,…
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Discitis – Infection of the Intervertebral Disc

After describing the main characteristics of the desease, the author presents several cases of discitis in order to illustrate the difficult diagnosis due to the misleading clinical picture. The desease…
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Methodologic and Clinical Aspects of the Prognosis of Schizophrenia

Since schizophrenia is perhaps the most debilitating mental illness, it is important to know the prognosis factors. It has long been believed that outcome of schizophrenia is almost inevitably poor.…
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Can We Die from Fear?

The relationship between stressful emotions and sudden cardiac death is sup­ported not only by anecdotal reports, but also by experimental, epidemiologic and clinical data. Links between emotional stress, neural control…
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Latest Views on Pathogenesis, Epidemiology, Clinical Picture and Diagnosis of Infective Endokarditis

Infective endocarditis is a disease with protean manifestations. The diagnosis is based mainly on the typical clinical signs and on a few laboratory parameters. The clinical and epide­miological aspects of…
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Corticospinal Tract Jitter

Corticospinal influences on distal and proximal muscles of the upper limb were stud­ied in 14 normal volunteers. The techniques of electrical and magnetic corticospinal tract acti­vation through intact scalp were…
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