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Of all medical sciences in Slovenia, occupational medicine has one of the longest traditions. It is not a mere coincidence that began to develop in Idrija as early as the beginning of the 18th century. The Idrija mercury mine, the second largest mine of the world after Almaden in Spain, was owned by the Habsburg dynasty for four centuries. The … Preberite več >>

Neuroleptics were discovered by chance in 1950. Since then, a substantial body of clinical experiences has been collected. The understanding of mechanisms of their action stimulated the development of new theories about the causes of mental disorders. Neuroleptics are symptomatic drugs, because they do not affect the principal causes of mental disorders. The authors give a brief historical review of … Preberite več >>

The object of this study was to determine reference levels of vitamin D and its metabolites in the sera of individuals with normal vitamin D metabolism. The measurements were done in compliance with the instructions for reference value determinations given by International Federation of Clinical Chemistry. The paper presents the nomenclature, physical and chemical properties, and physiology and pathologic physiology … Preberite več >>

Unstable shoulder is a common problem encountered most frequently in sportsmen. Modern treatment of this disorder requires solid knowledge of abnormal mechanics and pathology of unstable shoulder, which are dealt with in this paper. The diagnosis is based on clinical tests and noninvasive imaging techniques, the most widely used being ultrasound and the most useful magnetic resonance imaging. Arthroscopy is … Preberite več >>

Acquired cystic disease of the kidney is common in patients with chronic renal failure. The authors present prevalence and pathogenesis of the disease, which is not of a great clinical importance unless accompanied by its complications, especially malignant transformation. The incidence of renal cell carcinoma, which usually remains asymptomatic, is high. Ultrasound is screening method of choice for detecting acquired … Preberite več >>

Tuberculosis represents a great world public health problem due to its increased incidence and the advent of multidrug-resistant strains. Recent developments in molecular microbiology have raised hopes about the possibilities of new strategies for tuberculosis diagnosis. Nucleic acid amplification of target molecules to a detectable level is the best developed and the best analyzed system for detecting mycobacteria. A variety … Preberite več >>

The wealth of energies around us are detected by receptors transducing the physical stimuli in a train of nerve impulses. These are conducted to the perception centres in the CNS, where they elicit sensory impressions. Receptors of the somatosensory apparatus make sensory processing of tactile sensation, proprioception, pain and thermal sensation possible. The character of sensation is determined by the … Preberite več >>

In the present study the effects of either H1 antagonist chloropyramine or H2 antagonist famotidine were investigated in isolated Langendorff’s rat hearts. Ischemia lasted 60 minutes. Perfusion with either 10 μmol/L chloropyramine or 10 μmol/L famotidine was initiated 10 minutes before ischemia and lasted till the end of the experiments. Registered were left ventricular pressure, heart rate, Q, coronary flow … Preberite več >>

We set out to introduce serum markers into the diagnosis of coeliac disease as a substitute or supplement to small intestinal mucosa biopsy. At the Paediatrics Department of the Maribor Teaching Hospital, determinations of antigliadin (AGA-IgA and AGA-IgG) and antiendomysial antibodies are carried out in to asses the reliability of these coeliac disease markers in indicating the state of small … Preberite več >>