Spoštovani kupci!
Zaradi prenove spletne strani in prehoda na OJS spletna prodaja trenutno ne dela. Prosim, če sporočite, kaj bi radi kupili, na prodaja@medrazgl.si. Dopišite vaše ime in priimek, naslov ter način plačila (s predračunom, ob povzetju ali z gotovino, če prezvamete gradivo v živo v prostorih uredištva v času uradnih ur).
Hvala za razumevanje!
MENU
Anatomy
Anesthesiology
Biochemistry
Biomedical Informatics
Biophysics
Cell Biology
Clinical Cases
Dentistry
Dermatovenerology
Emergency Medicine
Family Medicine
Forensic Medicine
Gynecology and Obstetrics
Histology and Embryology
History of Medicine
Human Genetics
Hygiene
Infectious Diseases
Internal Medicine
Medical Deontology and Philosophy
Medical Psychology
Microbiology and Immunology
Neurology
Occupational Medicine
Oncology
Ophthalmology
Orthopaedics
Otorhinolaryngology
Pathology
Pathophysiology
Pediatrics
Pharmacology and Experimental Toxicology
Physical and Rehabilitation Medicine
Physiology
Psychiatry
Radiology
Social Medicine
Surgery
Toxicology
Research papers
Clinical research paper
Preclinical research paper
Sponsored articles
Archive » 2015 » 1 » | Archive » Medical field » Fields » Neurology »

Non-Motor Symptoms of Parkinson’s Disease

 
Abstract:

This post is also available in: English Slovenščina (Slovenian)

Parkinson’s disease is traditionally regarded as a movement disorder caused by the loss of dopaminergic neurons in the nigrostriatal system. However, we are becoming more and more aware that pathology of this disease is much wider than initially thought and that degeneration may involve many areas in both central and peripheral nervous systems. This is reflected in a wide spectrum of non-motor symptoms that involve sleep, psychiatric, cognitive, autonomic and sensory disorders. Non-motor symptoms occur in more than 98% of the patients with Parkinson’s disease. They can appear at anytime in the course of disease and are often present in the preclinical phase (pre-motor symptoms). The pre-motor symptoms can predate the onset of Parkinson’s disease and they could be used as biomarkers for identifying persons at risk for development of Parkinson’s disease. Early detection of Parkinson’s disease will be of considerable value when neuroprotective therapy becomes available. The non-motor symptoms become more frequent and more severe as the disease progresses. They often represent a huge burden for the patient and can cause a severe decrease in the quality of life. It is therefore very important to recognize and treat these symptoms, as this can significantly improve the patient’s well-being.

Authors:
Pavšič Katja, Pirtošek Zvezdan

Keywords:
Parkinson's disease, parkinsonism, non-motor symptoms, pre-motor symptoms

Cite as:
Med Razgl. 2015; 54 (1): 95–115.
© 2024 Društvo Medicinski razgledi | Na vrh strani / To top ↑