MENU
Anatomy
Anesthesiology
Biochemistry
Biomedical Informatics
Biophysics
Cell Biology
Clinical Cases
Dentistry
Dermatovenerology
Emergency Medicine
Family Medicine
Forensic Medicine
Gynecology and Obstetrics
Histology and Embryology
History of Medicine
Human Genetics
Hygiene
Infectious Diseases
Internal Medicine
Medical Deontology and Philosophy
Medical Psychology
Microbiology and Immunology
Neurology
Occupational Medicine
Oncology
Ophthalmology
Orthopaedics
Otorhinolaryngology
Pathology
Pathophysiology
Pediatrics
Pharmacology and Experimental Toxicology
Physical and Rehabilitation Medicine
Physiology
Psychiatry
Radiology
Social Medicine
Surgery
Toxicology
Research papers
Clinical research paper
Preclinical research paper
Sponsored articles
Archive » 2014 » 4 » | Archive » 2014 » 4 » Archive » Medical field » Fields » Internal Medicine »

Asthma and Sport in Adults

 
Abstract:

This post is also available in: enEnglish slSlovenščina (Slovenian)

Exercise-induced ­bronchoconstriction­ is­ defined­ as­ reversible­ narrowing­ of­ distal­ airways that­ follows­ vigorous exercise­ in­ the­ presence­ or­ absence­ of­ clinically­ recognised­ asthma.­ The­ prevalence­ in­ general­ population­ is­ 7–20%, in­ athletes­ even­ higher,­ around­ 50%. Water ­depletion­ at­ the­ level­ of­ airways­ is­ a­ reaction­ to­ increased­ minute ventilation­ and represents­ a­ stimulus­ to­ exercise-induced­ bronchoconstriction.­ There­ are­ two­ theories seeking­ to­ explain­ exercise-induced­ bronchoconstriction:­ thermal­ and­ osmotic.­ In­ the­ laboratory­ conditions,­ the­ establishment of­ the­ diagnosis­ can­ be­ difficult.­ The­ type­ of­ protocol­ used­ for­ diagnosis­ must­ consider­ mechanistic­ factors­ for exercise-induced­ bronchoconstriction.­ To­ elicit­ dehydration­ of­ the­ airway­ surface­ liquid­ and­ to­ cause­ a­ transient increase­ in­ its­ osmolarity,­ the­ rate­ of­ water­ loss­ must­ exceed­ the­ rate­ of­ return­ in­ the first­ 10­ generations­ of­ airways. In­ general,­ the­ drier­ the­ inspired­ air­ and­ the­ higher­ the ventilation­ sustained­ during­ exercise,­ the­ less­ likely­ a­ false negative­ test­ result­ will­ occur. There­ are­ two­ forms­ of­ bronchoprovocation:­ direct­ and­ indirect.­ They­ differ­ with respect to­ basic­ mechanisms­ of­ inducing­ bronchoprovocation.­ The­ management­ of­ exercise-induced bronchoconstriction­ should­ include­ both­ prevention­ and­ treatment­ directed­ toward­ the underlying­ asthma­ and­ bronchial­ hyperresponsiveness.­ Among­ the­ nonfarmacological components­ of­ treatment,­ high­ intensity­ warm­ up­ is recommended.
Authors:
Škrgat Sabina

Keywords:
exercise, asthma, treatment, exercise-induced bronchoconstriction

Cite as:
Med Razgl. 2014; 53 (4): 527–36.

Download PDF >>
© 2022 Društvo Medicinski razgledi | Na vrh strani / To top ↑