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The authors present a patient with severe coronary artery disease who suffered acute inferoposterior myocardial infarction. The first three days of rehabilitation were uneventful, but on the fourth day the patient showed a sudden onset of pulseless electrical activity. Cardiopulmonary resuscitation was unsuccessful and the patient died. The authors emphasize the role of bedside echocardiography for detection of mechanical complications … Preberite več >>

Respect for autonomy – one of the four basic ethical principles – is based on the right for self-determination. An autonomous individual should be offered all relevant information so that he/she can understand the consequences of various options, make free choices and im­plement his/her own decisions. Thus, respecting one’s autonomy involves assuming several ob­ligations, including the obligation to assure anot­her … Preberite več >>

This paper was written to mark the 175^th anniversary of birth of Arnold Rikli, famous Swiss healer, who is credited with pioneering mo­dern health tourism in Slovenia. In 1855, Rikli settled in the alpine region of Lake Bled to set up a health resort. His treatment methods which adhered to principles of natural healing exploi­ted the favourable effects of … Preberite več >>

The article defines and explains so­me terms and concepts of quality assurance and quality improvement of health care.… Preberite več >>

Physical principles of the description of fluid flow through a system of pipes and so­me mechanical properties of the blood circula­tion are put forward. As an example, the velocity field of the model vertebro-basilar junction is pre­sented. The influence of some geometrical parameters on the blood flow and on the deve­lopment of atherosclerotic changes is shown, proving thereby the importance … Preberite več >>

An ideal medical treatment for affec­tive disorders is not yet available. Specific needs of individual patients can be met by selecting from among a wide range of drugs on the market. The authors review literature on the use of anticon­vulsants in patients with affective disorders. They discuss various aspects of this therapy: treatment and prophylaxis of manic and depressive episo­des; … Preberite več >>

Multiple sclerosis is a chronic autoim­mune demyelinating disease. In the article, the epidemiological situation in the world as well as the prevalence and incidence of multiple sclero­sis in our country is presented. The role of geo­graphic, environmental and genetic factors on the development of multiple sclerosis is pointed out. The new insights into the complicated pathophy­siological process, the role of … Preberite več >>

Two polymorphic sites of the CYP1A1 gene, coding for cytochrome P4501A1 enzyme, have been discovered so far. One involves the 7^th exon of the coding region; a nucleotide chan­ge leads to amino acid replacement in the heme binding region of cytochrome P4501A1 (poly­morphism Ile/Val). Another site is in the 3′-flanking region of the gene, and results in the presence … Preberite več >>

The purpose of this study was to de­termine the diagnostic value of the lymphocyte blast transformation test in Lyme disease. Our laboratory results were compared with the diag­noses established by physicians. The course of the illness was followed in 213 individuals who­se blood samples were tested for cell immunity against Borrelia burgdorferi. All patients sho­wed clinical picture compatible with … Preberite več >>