Life and work of the Slovenian physician and politician Dr. Ivan Oražen (1869-1921) is closely related to the period during which he lived. As illegitimate child his youth was marked with poverty. When he got married into the brewing family Auer from Ljubljana, he became wealthy. But despite this he remained loyal to his own principles, he remained a patriot
The article describes ethical and law dilemmas that physicians encounter nowadays. After a short deontological and law review the author points out and descibes from the medical and deontological point of view three representative examples taken out from nowadays society (hunger strike, surgical split of conjoined twins and patients with anorexia nervosa) where there is an evident disharmony between physician’s
Schizophrenia is one of the most severe psychiatric disorders and carries a lifetime risk of 1%. The International Classification of Diseases and Related Health Problems, 10th Revision 461 (ICD 10), classifies the following forms of schizophrenia: paranoid, hebephrenic, catatonic, undifferentiated, residual, simple schizophrenia, and post-schizophrenic depression. The article describes most common paranoid and rare catatonic schizophrenia, their diagnostic guidelines, clinical
Neuroleptic malignant syndrome is a serious, life threatening complication of antipsychotic therapy with typical or atypical antipsychotics (neuroleptics). It is the rarest and the most serious of neuroleptic induced movement disorders characterized by rigidity, altered consciousness, fever and autonomic nervous system dysfunction. Two cases of neuroleptic malignant syndrome are presented. Clinical presentation, diagnostic workup, differential diagnoses, pathophysiology and treatment are
Several publications in scientific magazines try to revive the interest in the frequently overlooked importance of the variability and the consequences of blood pressure variability on cardiovascular events. Despite the fact that arterial hypertension is the most prevalent risk factor, which can be controlled by means of drugs, the development of target organ damage destruction and cardiovascular events has not
Wound management represents a great burden for the patients’ quality of life and also for the healthcare expenditures. The understanding of the complex cellular and molecular mechanisms involved in the healing process enabled the recent development in the field of wound dressing. One of the recent advances in the field is the negative wound pressure therapy. This modern wound dressing
Chronic kidney disease affects on average one of ten adults and is associated with high mortality and treatment costs in the world as well as in our country. Patients with diabetes, hypertension, cardiovascular disease and a known hereditary kidney disease in the family have the highest risk for development of chronic kidney disease. Smokers and obese people are at higher
Exocytosis, part of which is the merger of the vesicle and the plasma membrane, is characteristic for eukaryotic cells, which engage this process in a myriad of cell functions. For a long time it was believed that exocytosis was predominantly regulated by proteins, a view referred to as ‘proteocentric’. Only recently it was shown that many of lipids, previously considered
BACKGROUNDS. Ill-fitting footwear is an important risk factors for diabetic foot ulceration, especially in case of foot deformities and sensory neuropathy. The aims of the research were to investigate the validity of the three-dimensional foot scanning, to obtain data on the food size and shape in the patients with diabetes , to evaluate the necessity of marketing shoes of different
BACKGROUNDS. Treatment of total edentulism with implant-supported overdenture is an established alternative to the conventional removable denture, especially in the case of poor anatomical conditions in the mandible. The aim of our study was to estimate the difference in satisfaction based on the quality of life aspect in totally edentulous Slovenian patients treated with mandibular implant-supported overdentures or conventional removable
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