The median annual mortality from snow avalanches registered in the 17 ICAR countries from 1981 to 1998 was 146. Swiss data document a mortality rate of 52.4% in completely-buried, versus 4.2% in partially-, or non-buried, persons (n=1,886). The survival probability of completely-buried victims in open areas (n=638) plummets from 91% at 18 min after burial to 34% at 35 min … Preberite več >>
It is well documented that exposure to a hypoxic environment affects visual and auditory perception and attenuates cognitive function in humans. Since the perception of thermal stimuli is indispensable for appropriate behavioral protection against cold in both low and high altitudes, the present study examined if and how hypoxia affects the perception of cold stimuli in humans. The perception of
Altitude acclimatization and altitude exercise are physiologically demanding for the body. During exercise at high altitudes, energy and fluid needs are almost difficult to satisfy with normal food intake. An inappropriate thirst and appetite response can contribute to rapid dehydration, glycogen depletion and weight loss unless adequate amounts of food and fluid are ingested. Dehydration may intensify the symptoms of
Breast cancer is a serious health care problem, since it is the most common type of cancer in women and a leading cause of death from cancer. A diagnostic approach using triple assessment of breast cancer has been introduced in many institutions worldwide, including Slovenia. It encompasses clinical examination, mammography and fine needle aspiration biopsy (FNAB), which allows the aspiration … Preberite več >>
The prevalence of gastroesophageal reflux disease in the Western world is rising and is now up to 20%. The main etiological factors are an incompetent anti reflux barrier and/or unsuccessful luminal clearance mechanisms. Gastroesophageal reflux disease can be divided into three groups: 70% of patients have the non-erosive form, 30% the erosive form, and 10% of former patients with the … Preberite več >>
In the article the comprehensive geriatric assessment (CGA) – a new systematic approach to the collection of patient data that allows appropriate evaluation of chronic diseases, geron- tologic syndromes and functional impairment, is presented. According to CGA, first subjective and objective database is collected, then integrated into an assessment (particular attention is focused on the nine main problem issues), and
The author presents the bone biopsy: indications for the procedure, laboratory treatment of the sample and bioptic histological pictures of major metabolic bone diseases. Bone biopsy retains the most important role in nephrology for the determination of variants of renal bone disease, a consideration which is important for therapeutic decisions. In endocrinology, it is important for the diagnosis of (mostly) … Preberite več >>
The eye and, the sensory organ for vision, develops from the sensory placodes in the ectodermal germ layer like the other sense organs, in response to induction from the central nervous system. A single eye field separates into two optic primordia after sonic hedgehog stimulus expressed in the prechordal plate. Eye development is first evident at the beginning of the … Preberite več >>
Negative feedback is one of the most difficult topics in physiology, possibly because descriptive thinking is useless. Instead, to analyse single constituents quantitatively or semiquantitatively, causal thinking is mandatory. By using analogue simulation, the author tries to show the basic properties of negative feedback. The characteristics of an ideal negative feedback – operating without any appreciable delay – are shown.
Hemodialysis is the most widely used method of renal replacement therapy in end-stage renal disease. It requires a reliable permanent vascular access and arteriovenous fistula (AVF) is the most commonly used method. Among other complications, it may cause hand (palm and fingers) ischemia (incidence 1–10%) as a result of altered hemodynamic circumstances in the area. Hand ischemia is manifested by
Background: Endometriosis involves an appearance of endometriotic tissue with all of its histological and functional properties outside the uterine cavity. The frequency of endometriosis in women of reproductive age without symptoms and signs of disease remains unknown. This disease is probably the most frequent cause of infertility and impaired fertility.
Objective: The objective of our study was to estimate the