Endometrial cancer and endometriosis are very common estrogen-dependent diseases. Endometrial cancer is the third most common cancer in women, while endometriosis affects around 15–20% of women of reproductive age and…

Methicillin-resistant Staphylococcus aureus (MRSA) was first reported over 30 years ago. Within a decade, MRSA was established as an important nosocomial pathogen in both the adult and pediatric populations. MRSA…

Amyloidosis is a group of diseases for which extracellular deposition of a fibrillary protein called amyloid is typical. There are many types of amyloidoses. Secondary amyloidosis is con­nected with pre-existing…

Nasopharyngeal carcinoma is as rare in Slovenia as in other Western countries. Given the etiopathogenetic interdependence of viral infection, neoplastic transformation and host immune response, nasopharyngeal carcinoma is a unique…

Neonatal unconjugated hyperbilirubinemia continues to be one of the most frequent and puz­zling problems in neonatology. Ten years ago, the guidelines for management of neonatal unconjugated hyperbilirubinemia were changed when…

The term neurovascular coupling denotes the relationship between neuronal activity and regional cerebral blood flow. A method that would enable analysis of neurovascular coupling in humans is still to be…

Sex might be an important factor in the development of certain ischemic diseases of the heart. We tried to assess the effects of treating rats with estradiol or testosterone on…

Histamine is a biogenic amine known as a primary mediator of allergic reactions. In brain, its role involves neurotransmission. Researches in the field of histamine pharmacokinetics have shown that antidepressants…

Based on experimental data, it is widely believed that any extended climbing rope fall may cause life-threatening injuries when using a sit harness alone. This is mainly due to the…

The median annual mortality from snow avalanches registered in the 17 ICAR countries from 1981 to 1998 was 146. Swiss data document a mortality rate of 52.4% in completely-buried, ver­sus…

It is well documented that exposure to a hypoxic environment affects visual and auditory perception and attenuates cognitive function in humans. Since the perception of thermal stim­uli is indispensable for…

Altitude acclimatization and altitude exercise are physiologically demanding for the body. During exercise at high altitudes, energy and fluid needs are almost difficult to satisfy with normal food intake. An…

Breast cancer is a serious health care problem, since it is the most common type of cancer in women and a leading cause of death from cancer. A diagnostic approach…

The prevalence of gastroesophageal reflux disease in the Western world is rising and is now up to 20%. The main etiological factors are an incompetent anti reflux barrier and/or unsuc­cessful…

In the article the comprehensive geriatric assessment (CGA) – a new systematic approach to the collection of patient data that allows appropriate evaluation of chronic diseases, geron- tologic syndromes and functional…

The author presents the bone biopsy: indications for the procedure, laboratory treatment of the sample and bioptic histological pictures of major metabolic bone diseases. Bone biopsy retains the most important…

The eye and, the sensory organ for vision, develops from the sensory placodes in the ectodermal germ layer like the other sense organs, in response to induction from the central…

Negative feedback is one of the most difficult topics in physiology, possibly because descrip­tive thinking is useless. Instead, to analyse single constituents quantitatively or semiquantitatively, causal thinking is mandatory. By…

Hemodialysis is the most widely used method of renal replacement therapy in end-stage renal disease. It requires a reliable permanent vascular access and arteriovenous fistula (AVF) is the most commonly…

Background: Endometriosis involves an appearance of endometriotic tissue with all of its his­tological and functional properties outside the uterine cavity. The frequency of endometriosis in women of reproductive age without…

The article reviews cognitive impairment and mental disorders in Parkinson's disease, which often accompany movement disorders and contribute to patients disability. Specific clinical picture as well as pharmacological treatment of…

A surgical procedure is a stressful event that triggers an inflammatory response. An exces­sive pro-inflammatory response is associated with a worse prognosis, while on the other hand an excessive anti-inflammatory…

Teaching about medical ethics and deontology, included in curriculums of most important medical faculties in Europe and USA, has a long and successful tradition in Slovenia too. Con­sidering that we…

The incidence of colorectal cancer (CRC) in Slovenia is increasing, the steepest rise occur­ring over the age of 50. Adenoma is regarded as a precancerous lesion, which develops because of…