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The Role of Hydroxysteroid Dehydrogenases in the Regulation of Estrogen and Progestagen Activity: a Case of Endometrial Cancer and Endometriosis
Endometrial cancer and endometriosis are very common estrogen-dependent diseases. Endometrial cancer is the third most common cancer in women, while endometriosis affects around 15–20% of women of reproductive age and…
Read more ›Genetic Background of the Staphylococcus aureus Methicillin Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) was first reported over 30 years ago. Within a decade, MRSA was established as an important nosocomial pathogen in both the adult and pediatric populations. MRSA…
Read more ›Secondary Amyloidosis with Inflammatory Bowel Disease and Nephrotic Syndrome
Amyloidosis is a group of diseases for which extracellular deposition of a fibrillary protein called amyloid is typical. There are many types of amyloidoses. Secondary amyloidosis is connected with pre-existing…
Read more ›Carcinoma of the Nasopharynx
Nasopharyngeal carcinoma is as rare in Slovenia as in other Western countries. Given the etiopathogenetic interdependence of viral infection, neoplastic transformation and host immune response, nasopharyngeal carcinoma is a unique…
Read more ›Update on and Clinical Management of Neonatal Unconjugated Hyperbilirubinemia
Neonatal unconjugated hyperbilirubinemia continues to be one of the most frequent and puzzling problems in neonatology. Ten years ago, the guidelines for management of neonatal unconjugated hyperbilirubinemia were changed when…
Read more ›The Analysis of Neurovascular Coupling by Visual Evoked Potentials and Doppler Sonography
The term neurovascular coupling denotes the relationship between neuronal activity and regional cerebral blood flow. A method that would enable analysis of neurovascular coupling in humans is still to be…
Read more ›Effects of Sex Hormones on Postischemic Damage of Isolated Rat Hearts
Sex might be an important factor in the development of certain ischemic diseases of the heart. We tried to assess the effects of treating rats with estradiol or testosterone on…
Read more ›The Influence of Amitriptyline and Sertraline in Vitro on the Kinetics of Exogenous Histamine in Cat Blood
Histamine is a biogenic amine known as a primary mediator of allergic reactions. In brain, its role involves neurotransmission. Researches in the field of histamine pharmacokinetics have shown that antidepressants…
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