Cardiovascular diseases are still the leading cause of morbidity and mortality in the developed world. Besides well-known classical risk factors for atherosclerosis, more and more intention has in recent years…

BACKGROUNDS. Celiac disease is a systemic, immune-mediated disease, triggered by the ingestion of gluten-containing grains in susceptible individuals. Recently there have been changes in diagnosis of celiac disease, mainly due to…

The etiology and pathophysiology of spontaneous cervical artery dissection are largely unknown. Its etiology is likely multifactorial, and primary arteriopathy is most probably involved. An association with migraine has also…

Despite profound advances in the treatment of ischemic heart disease with medications or invasive procedures during the past 30 years, ischemic heart disease remains the main cause of mortality and morbidity…

In view of increased prevalence of heart failure and the persistent unacceptably high morbidity and mortality associated with this condition despite current pharmacological treatments, novel therapeutic approaches have been sought.…

The treatment of liver injuries is a special challenge for surgeons. We have modern treatment techniques, but severe liver injuries still represent a high percentage of the overall mortality rates. Blunt…

Pulmonary hypertension is a pathophysiological and a haemodynamic state that can be observed in different clinical conditions. Although they all share elevated pressure in the pulmonary circulation, the underlying mechanism,…

Acute pulmonary thromboembolism is a complication of deep venous thrombosis. The incidence of pulmonary embolism increases with age and is higher in persons with risk factors for deep venous thrombosis.…

Respiratory diseases are one of the major public health problems as they represent a significant cause of morbidity and mortality. Among more than 40 different respiratory diseases the highest global…

Pneumoconioses are still a common cause of chronic lung disease. The term »pneumoconiosis« refers to reactions of the lungs to inhaled mineral or organic dusts, and resultant alteration in their…

Iodine is a constituent element of thyroid hormones which regulate many metabolic processes. Optimal daily intake of iodine for adults ranges between 150 and 250 μg, while during pregnancy and…

The digital world of computer technologies is becoming increasingly important in all fields of science, including medicine. Many new approaches that seemed to be pure fantasy decades ago are now…

Leukemias are malignant neoplasms of the hematopoietic system. They are characterized by the accumulation of a malignant clone of cells in the bone marrow and blood, which are afunctional. These…

Amyloidosis is a group of diseases for which extracellular deposition of a fibrillary protein called amyloid is typical. There are many types of amyloidoses. Secondary amyloidosis is con­nected with pre-existing…

The prevalence of gastroesophageal reflux disease in the Western world is rising and is now up to 20%. The main etiological factors are an incompetent anti reflux barrier and/or unsuc­cessful…

In the article the comprehensive geriatric assessment (CGA) – a new systematic approach to the collection of patient data that allows appropriate evaluation of chronic diseases, geron- tologic syndromes and functional…

Hemodialysis is the most widely used method of renal replacement therapy in end-stage renal disease. It requires a reliable permanent vascular access and arteriovenous fistula (AVF) is the most commonly…

The incidence of colorectal cancer (CRC) in Slovenia is increasing, the steepest rise occur­ring over the age of 50. Adenoma is regarded as a precancerous lesion, which develops because of…

VDD pacing systems are an alternative to DDD pacing systems in patients with atrioven­tricular (AV) block and normal sinus node function. Our study compared atrial sensing, ventricular stimulation threshold, AV…

Acute hepatic porphyrias are rare disorders of heme metabolism and can potentially be let­hal. Diagnosis is based on the clinical presentation and laboratory analysis of urine. Adequate and early treatment…

We present a patient with acute myocardial infarction, by whom recurrent attacks of ventricular fibrillation 15 days after the infarction appeared. All attacks had to be terminated by defibrillation. Various…

Atherosclerosis is a slowly progressing degenerative disease of the arterial wall. Several risk factors, including cigarette smoking, precipitate its development. The purpose of the study was to investigate atherosclerotic morphologic…

The gastrinoma was first described by the surgeons Zollinger and Ellison in 1955. The basic characteristics of this disease include an endocrine gastrin-secreting tumor of the gastrointestinal tract, gastric hypersecretion…

Acquired cystic disease of the kidney is common in patients with chronic renal failure. The authors present prevalence and pathogenesis of the disease, which is not of a great clinical…