Since 1962.

Internal Medicine

The Reliability of Serum Antigliadin and Antiendomysial Antibodies as Indicators of Children with Small Intestinal Mucosa Atrophy in Coeliac Disease

We set out to introduce serum markers into the diagnosis of coeliac disease as a substitute or supplement to small intestinal mucosa biopsy. At the Paediatrics Department of the Maribor…
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Gallstone Ileus – Bouveret’s Syndrome

The article presents a female patient that was operated in acute state for gallstone ileus without a prior anamnesis having been taken. Due to multiple stones, the ileus recurred with…
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Early Functional and Morphologic Changes of Arterial Wall in Diabetes

Diabetes mellitus is an important risk factor for atherosclerosis. The aim of this study was, first, to determine whether young patients with insulin-dependent diabetes mellitus display atherosclerotic changes at the…
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Subclavian Vein Catheterization

Central venous catether is for many years accompanist of intensive treatment. In the article are described supraclavicular subclavian vein approach by Yoffa and medial infraclavicular approach. Both are among the…
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Acute Pancreatitis

Regardless of its etiology, acute pancreatitis is a severe, even life-threatening disease. The etiologic agents in patients with acute pacreatitis are generally known, yet the exact pathogenetic mechanisms, which trigger…
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»Cylindricality« as a mechanism of quality of left ventricle action

The endocardial surface and the volume of the left ventricle were determined experimentally by an original noninvasive method with the goal of understanding the mechanism of the influence of the…
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Arterial Hypertension-Induced Changes in Blood Vessels and Blood Structure

Arterial hypertension is one of the major risk factor predisposing to atherosclerosis. Since elevated blood pressure is part of endocrine metabolic syndrome, hypertensive patients have many other risk factors predisposing…
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Spontaneus Bacterial Peritonitis – Frequent and Often Unidentified Complication in Patients with Decompensated Liver Cirrhosis

Spontaneous bacterial peritonitis is a hematogenic infection of ascitic fluid occurring in immunodeficient patients with decompensated liver cirrhosis. The most common causative organisms of this monobacterial infection include enterobacteria and…
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Artificial Ventilation at Home

Artificial ventilation means that the air is forced artificially – by apparatus (ventilator) – into the lungs of the patient who is unable to breathe for himself due to his…
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An unusual cause of amenorrhea in an adolescent girl

Amenorrhea in younger women is a fairly common problem encountered both by general practitioners, gynaecologists and school doctors. The spectrum of its causes is very broad. Fortunately, the disease is…
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Solitary rectal ulcer syndrome

Solitary rectal ulcer syndrome is a rare chronic condition which became more widely known in the seventies after its histological criteria had been established. In nearly all cases, solitary rectal…
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Something about microcirculation

The paper outlines the fundamentals of morphology and the function of microcirculation, and presents the physiological and pathophysiological aspects of microcirculation. Changes in microcirculation due to hypoxia resulting from involvement of great arteries…
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Correlation between QTc interval changes and results of thrombolytic therapy in patients with acute myocardial infarction

The aim of this study was to find out whether changes in the QTc interval duration in patients with acute myocardial infarction are related to the effectiveness of thrombolytic therapy.…
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An unusual combination of acute myocardial infarction and aortic arch dissection

  the authors report on a rare case of acute myocardial infarction associated with dissection of the aortic arch. Treatment and differential diagnosis are presented. Early administration of fibrinolytic agents is undoubtedly…
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Severe status asthmaticus with atelectasis of the entire pulmonary lobe

The author presents a female patient with severe status asthmaticus. He presents pathogenesis, pathophysiology and potential complications of the disease and stresses the importance of clinical evaluation of the patient…
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The role of oxygen free radicals in some physiological and pathological processes

Oxygen free radicals play an important role in many processes: they are involved in various phases of the inflammatory process and therefore take part in the defence of the organism.…
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Clinical entities in the postinfraction period

Clinical entities that most commonly complicate the early postinfraction course and have adverse effects on prognosis include myocardial ischemia, heart failure and arrhythmias. The objective of the study was to…
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The value of some stress tests in predicting hypertension

We studied 62 young healthy volunteers, mostly students, with the mean age of 23,7 years. They were devided into a group with positive family history of hypertension (group A, N=27)…
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Urinalysis – Urine Macroscopic and Microscopic Examination and Urine Reagent Dipstick Test

Urinalysis is a very simple and inexpensive test which, when correctly interpreted, is an invalu­able diagnostic tool in the diagnosis if many urologic and non-urologic diseases. This review article presents…
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Modern Principles in the Treatment of Aortic Valve Stenosis in the Elderly

Degenerative aortic stenosis is the second commonest heart valve disorder in the adult pop­ulation in the developed world. The basic pathologic process is aortic valve sclerosis. The incidence and prevalence…
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Non-steroidal Antiinflamatory Drugs (NSAIDs) and the Kidney

Non-steroidal antiinflammatory drugs (NSAIDs) are among the most widely utilized thera­peutic agents today. The main mechanism of their action is via inhibition of cyclooxygenase, the enzyme involved in prostaglandin synthesis.…
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Acute complications of diabetes

Acute complications of diabetes are life-treatening conditions requiring immediate medical assistance. Although they are responsible for a rather small proportion of deaths in diabetic patients, the mortality rates associated with…
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Reproducibility of fibrinolytic response to venous occlusion in healthy volunteers

Fibrinolytic response to venous occlusion is used to asses efficiency of fibrinolytic system. All factors that might influence fibrinolytic response are not known. The venous occlusion was preformed twice within…
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Venom hiposenzitization as prophylaxis against anaphylactic reaction

We studied 44 patients receiving venom immunotherapy. Among the patients who suffered insect sting during the immunotherapy period, the number of subjects responding only by local reaction (60%) or mild…
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