Neurotrophins are a subgroup of growth factors acting within the nervous system. They are small proteins forming a family of several members. Among these, NT-3 is the most abun­dantly distributed…

The contribution focuses on one of the more recent immunosuppressive drugs, mycophe­nolate, which is available as mycophenolate mofetil and sodium mycophenolate. The active substance of both compounds is mycophenolic acid.…

The glomerular filtration rate (GFR) is the main indicator of kidney function and GFR esti­mation is essential for the evaluation of patients with chronic kidney disease. In clinical practice, serum…

One of the essential elements of healthcare evaluation is the assessment of health-related quality of life. Health-related quality of life refers to how health impacts an individual's ability to function…

In the past ten years, development of ultrasound diagnostic technology has been very fast, especially in the field of three- and four-dimensional ultrasound. The purpose of this arti­cle is to…

Glaucoma is a chronic progressive optic neuropathy. Glaucoma is the second leading cause of irreversible blindness. Therefore, detection of structural optic nerve head and retinal nerve fiber layer changes and…

Rupture of abdominal aortic aneurysm is a potentially fatal event, occuring quite frequently in older men with uncontrolled hypertension. Because of nonspecific symptoms, such as abdominal and back pain, the…

The paper gives some basic informa­tion about the legislation governing obligations and benefits related to sick leave. The methods of sick leave data collection and analysis are presented, as well…

The mechanisms of deleterious effects of exposure to low and high frequency electro­magnetic fields (electromagnetic effects) in humans, especially hypersensitivity to 50 Hz electromagnetic fields with field power under 50…

Clinical hematology is the field of med­icine most closely related to immunology, since pathologically altered cells and other components of the immune response circulating in the blood form the basis…

Preterm delivery is still one of the main causes contributing a great deal to the perina­tal morbidity and mortality. Preterm birth of the child can be postponed, or at least…

The paper presents the metabolism of bilirubin and consequences of its toxic effect on new-born's brain. Increased production or decreased excretion of bilirubin, or a combina­tion of both, may be…

Electroporation is a process, which causes transient high-permeability of the cell membrane due to application of electric field. In the state of high-permeability, membrane allows different kinds of small and…

The purpose of this prospective study was to determine the potential effects of various factors on blood pressure (BP) levels in 40 pa­tients treated by haemodialysis. A 48-hour non-in­vasive ambulatory…

Antidepressants are known to influence the kinetics of histamine. The purpose of this study was twofold: to determine the influence of various doses of antidepressants fluvoxamine and mapro­tiline on induced…

The purpose of the study was to evaluate the results of operative reconstruction of the foot with a musculocutaneous latissimus dorsi free flap. At the Department of Plastic Surgery and…

The author reports a patient with acute liver and kidney failure diagnosed on his retur­ning from 14-day trip to Brasil, where he had been exposed to various risk factors for…

The article presents some facts about vegetarian diet, its influence on child develop­ment, possible complications and their preven­tion. A vegetarian diet, if properly selected, can meet all the requirements of…

The supracondylar fractures of the hu­merus are the most common type of elbow fractures in children. They occur in either extension or fle­xion pattern. Both patterns have three types distin­guished…

Patients with ovarian cancer are trea­ted individually. The basic method of treatment is the operation, precisely revealing the spread of disease and removing as much of the tumor as possible.…

The advent of ultrasonography and computed tomography has facilitated the ima­ging of kidneys in patients with chronic renal fai­lure. Patients with diffuse renal parenchymal disease present with small, shrunken end-sta­ge…

The recent technical development of echocardiography, especially transesophageal echocardiography, made the diagnosis of patent foramen ovale in adult life possible. The defect pre­disposes the patient to paradoxical embolism and is…

Apoptosis, named as programmed cell death, represents one form of cell death and has a crucial role in the tissue homeostasis. Be­sides this, apoptosis is involved in a number of…

Collateral sprouting of axons in the pe­ripheral nervous system is a branching out­growth of new axon terminals from non-injured axons into adjacent denervated regions of tar­get tissue. The initiation of…