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Nutrition of the Critically Ill

Malnutrition presents a major problem in several patients treated in intensive care unit (ICU). Extreme body reserve exhaustion influence s morbidity and mortality and prolongs hospi­tal stay. Therefore nutrition of…
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The Contribution of Nobel Prizewinners to the Development of Medicine in the First Half of the 20th Century

The article discusses the significance of various natural science discoveries in the develop­ment of medicine during the first half of the 20th century. Discoveries in various areas of natural science,…
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Chronic Obstructive Lung Disease (COPD)

The article presents the diagnosis, management, and prevention of chronic obstructive lung disease. It is written depending on the Global initiative for chronic obstructive lung disease conducted by US National…
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Clinical Significance of Ankle-Brachial Index

The ankle-brachial index is the ratio between systolic arterial pressures measured on the arms and the ankles. It is a highly sensitive and specific test for detecting peripheral arterial occ­lusive…
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Is Gender Difference in Development of Athlete’s Heart Related to 24-Hour Blood Pressure?

Long term athletic training is associated with an increase in left ventricular diastolic cavity dimensions, wall thickness, and mass. These changes are described as the »athlete's heart«. In men, athlete's…
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Comparison of Endothelial Function and Magnetic Resonance Characteristics of Vessel Wall among Patients with Classic and Dilatative Atherosclerosis

Background. Dilatative atherosclerosis is a rare form of degenerative process manifested by arterial aneurysms. It is believed that endothelial dysfunction is involved in dilatative athero­sclerosis. For estimation of systemic endothelial…
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Vaginal Birth after Cesarean Section

Over centuries there has been an unanswered question about vaginal birth after cesarean section. It is still connected with fear and uncertainty among patients and doctors. In 1916, Craign stated:…
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Normal Development and Abnormalities in the Development of Human Embryo

Human embryology is the science dealing with the development of the embryo and fetus from fertilization to birth. Development begins with fertilization, the process by which the male gamete, the…
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Disagreement between Doctor and the Patient During the Consultation

Communication with patients presents an important part of a physicians' work. The dis­agreements that appear during the consultation process, can affect quality of care. This is the reason why we…
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Herpesviruses and their Oncogenic Activity

The first human tumour virus, virus Epstein-Barr, was discovered in 1964 in Burkitt's lym­phoma cells. Oncogenic viruses are important for two main reasons. Firstly, approximately 15% of human cancer incidence…
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Anaesthesia in Patients with Myasthenia Gravis

Myasthenia gravis is an autoimmune disorder of the motor plate. The degree of reduction in the number of functional acetylcholine receptors correlates with the severity of myasthenia gravis as manifested…
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Foot Pain in Diabetic Patients

Assessment of pain, disability, and activity limitation was made with the Foot Function Index in healthy volunteers, diabetic patients without symptomatic neuropathy and diabetic patients with symptomatic neuropathy. The Foot…
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Indicators of Activated Coagulation in Patients with Venous Thrombosis and Mutation in the Genes for Prothrombin and Factor V

Mutation in the prothrombin gene (G20120A) and in the factor V gene (G1691A), which is manifested as resistance to the activated protein C (nAPC), are important risk factors for throm­boembolic…
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Dengue in Slovene Travellers Returning from the Tropics

Dengue fever has reemerged in the past 20 years and expanded to new geographic regions. Together with its causative agents (dengue viruses) and the vectors (Aedes mosquitoes), the epidemic activity…
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Breaking Bad News

Breaking bad news is one of the most difficult challenges in doctor-patient communication. It is very important, however, to both the quality of the patient's life and the future connection…
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Surgical Treatment of the Knee Cartilage Lesions

Due to its specific structure, articular cartilage has a limited regenerative ability. Even small lesions on the articular surface progress to an osteoarthritic deformation of the joint, with the end…
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The Ratio Between Sympathetic and Parasympathetic Activity During Head-up Tilt Table Test

Introduction. Neurocardiogenic syncope is the most frequent transitional form of loss of  onsciousness, which is caused by inappropriate triggering of the Bezold-Jarisch reflex. Most commonly, the triggering agent is an…
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The Role of the Posterior Tibial Tendon in the Adult Acquired Flatfoot

Flatfoot involves a complex change in the foot architecture with a lowered medial longitudinal arch and a hindfoot eversion. It is observed in one fifth of the adult population. A…
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Obstacles to Adherence to Treatment

Adherence to treatment is especially important for patients with a chronic illness. The emphasis is on the active cooperation of the patient in the treatment process, not just his passive…
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Usage of Thermotest

Modern neurophysiological methods (including the accurate psychophysical Marstock method) were used to determine sensitivity to heat, cold, and pain due to heat and cold (specific thermal and pain sensitivity) in…
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The influence of nicardipin and its enantiomers on enteral absorption of digoxin in guinea pig in vivo

Simultaneous administration of digoxin and calcium channel blockers results in increased plasma levels of digoxin. One of the possible mechanisms of this interaction could be a changed enteral absorption of…
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Percutaneous Aortic Valve Replacement: New Way of Treating Aortic Stenosis

Successful aortic valve replacement in the setting of aortic stenosis leads to dramatic improve­ments of the patient's clinical condition and wellbeing. Standard surgical aortic valve replace­ment is a relatively safe…
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Immunization of Children with Renal Disease

The article presents the recommendations for immunization of children with chronic kid­ney disease of higher stages and children with idiopathic nephrotic syndrome. These chil­dren are in some cases more susceptible…
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Insulin Resistance in Patients with Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrine disease in fertile women. It is also closely associated with insulin resistance (IR). The purpose of this trial was to inves­tigate…
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