Survival curves are used to describe the proportion of subjects alive through time. Since some of the data on survival are usually censored, special methods are needed to estimate the…

Peptide antibiotics are a very heterogenic group of antibiotics. Among them we differ cyclic, linear, non-substituted or substituted peptide antibiotics. The main feature of almost all pep­tide antibiotics is their…

A simple method of thoracentesis with an ordinary 16 gauge intravenous needle has been described. The method is simple and inexpensive. 62 thoracenteses using this method were performed in outpatient…

Myonuclei of mamalian skeletar muscle fibers are packed at much higher density in the neu­romuscular junction region than in the extrajunctional parts of the fiber. Slow muscle fibers are electromechanically…

Treatment of male infertility using the technique of intracytoplasmic sperm injection brought about a basic change in the possibilities of male infertility treatment. The described method of microsurgical egg fertilization…

The intermediate mesoderm gives rise to the kidney. Three pairs of kidney make an appear­ance in succession during development: pronephros, mesonephros and metanephros or permanent kidneys. Permanent kidneys develop from…

The author presents comprehensive long-term treatment of a patient with congenital bilateral malformation of the tibia. He hopes that the encouraging result presented will challenge other investigators to further refine…

The generation of arachidonic acid metabolites is associated with the activation of a wide range of mammalian cell types, and these compounds are involved in the regulation of a number…

The author deals with postoperative pain control, and defines pain in general. Several factors determing the intensity and duration of postoperative pain are presented. Surgery involving no protection against nociception…

Hip dysplasia may in the long term result in joint cartilage degeneration and ostheoarthrosis development. Clinical, radiographic, but also biomechanical assessment are important in the examination of dysplastic hips, the…

Analgesics are widely used drugs. Some of those belonging to the nonopioid group are also available as over-the-counter drugs. Acetylsalicylic acid (Aspirin®) and paracetamol, for exam­ple, are found in almost…

The most common illicit drugs in Slovenia that lead to poisoning requiring medical atten­tion are heroin, cocaine, meth-/amphetamines, cannabis, gamma-hydroxybutyrate and lyser­gic acid diethylamide. Heroin has an inhibitory activity and…

The article deals with the pharmacodynamics, pharmacokinetics, clinical presentation, dia­gnosis and treatment of selected groups of psychotropic drugs, namely benzodiazepines, monoamin oxidase inhibitors, cyclic antidepressants and second generation serotonergic anti­depressants.…

Epigenetic DNA modifications participate in genome regulation. These marks modulate the gene expression pattern and, on the whole genome scale, provide a cell-specific expression profile. They are pivotal to development,…

As the etiology of community-acquired pneumonia is generally unknown at the beginning of treatment, the initial antimicrobial ther­apy is empirical. The aim of this retrospective study was to assess the…

Hormonal factors are subtile regula­tors of bone metabolism. Together with the ge­netic factor, diet and exercise they are involved in the formation, maintainance and remodelling of the bone. In addition…

Echocardiography has an established role in evaluation of patients with infective endo­carditis. Positive echocardiogram is one of the Duke's major critera for infective endocarditis. Transthoracic and transesophageal echocar­diography can localize…

Familial hypercholesterolemia, an inheritable metabolic disorder, is the most pow­erful risk factor for the accelerated atheroscle­rosis. Mean intima-media thickness of carotid arteries was determined with B-mode ultra­sonography in 28 young…

In a muscle fibre, regulation of synthesis of motor endplate macromolecules changes during ontogenetic development. Immature early postnatal muscles of rat can synthesize the asymmetric forms of acetylcholinesterase (AChE) and…