Since 1962.

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Extracellular Vesicles and their Clinical Potential

Extracellular vesicles are a heterogeneous population of membrane vesicles, released from cells both in vivo and in vitro, with an important role in intercellular communication. They have been isolated from…
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Treatment of Bone Metastases

Bone metastases are significantly more common than primary neoplasms. Solid tumors, which spread to the bone most frequently, originate from the breast, prostate, thyroid gland or kidney cancer. These metastases…
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Effects of Occupational Activity in Pregnancy and Sick Leave on Preterm Birth Risk

Threatened preterm birth is the third most common cause of sick leave during pregnancy in Slovenia. There is no evidence that sick leave may reduce the risk of preterm birth.…
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Lumbosacral Injuries in Classical Ballet Dancers

The most likely risk factor for lumbosacral injuries in classical ballet dancers is hyperlordosis. Its development may be affected by weak abdominal muscles, holding the back too straight in the…
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Diagnostic Approach in a Patient with Gastrointestinal Stromal Tumour

Gastrointestinal stromal tumours (GIST) are mesenchymal tumours of the gastrointestinal tract. They are rare and represent about 1% of all malignancies in this area. They can occur anywhere in the…
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Life-Threatening Haemorrhage Due to a Spontaneous Aneurysm Rupture of the Lienal Artery in a Young Patient With Ehlers-Danlos Syndrome Type IV

Ehlers-Danlos syndrome type IV or vascular type is a rare connective-tissue disorder caused by impaired collagen III synthesis. It occurs due to the mutation in the COL3A1 gene, which is inherited…
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Laparoscopic Insertion of Peritoneal Dialysis Catheter

Peritoneal dialysis is a generally accepted method for management of renal failure in chronic and acute renal failure. A multidisciplinary team manages patients on peritoneal dialysis with nephrologist and surgeon…
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Treatment of Aortic Stenosis

Aortic stenosis is the most common structural disease of the heart. The second most common heart surgery is treatment of aortic stenosis by replacing the aortic valve with a prosthetic…
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Acute Pancreatitis

Acute pancreatitis is an unpredictable disease with a range of clinical courses. It is one of the most common diseases of the gastrointestinal tract with increasing annual worldwide incidence. The…
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Surgical Treatment of Lymphedema

Treatment of lymphedema requires integrated and extensive management in several steps. Surgical treatment follows conservative therapies when adequate results were not obtained. It is individually planned and requires long-term postoperative…
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Transition from Pediatric to Adult Healthcare: a Look at the Challenges and Needs of People with Epilepsy and Their Families

Providing health care to youth requires special attention to their developmental needs and characteristics. This applies especially to those who are chronically ill and find themselves on the verge of…
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Incretin System in Polycystic Ovary Syndrome: A Basis for a New Treatment Strategy in Specific Subgroups of Women with Polycystic Ovary Syndrome with High Metabolic Risk

Polycystic ovary syndrome is a common endocrine disorder which affects 15–20% of women in reproductive age. It is characterised by disturbances in the menstrual cycle and hyperandrogenism. These women are…
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The Importance of Breastfeeding

Breast milk is the ideal source of nutrition for newborns and infants because of its composition which is adapted to the child’s needs. It also provides a wide range of…
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Magnetic Resonance Imaging of the Fetal Central Nervous System

Magnetic resonance imaging is rapidly becoming a valuable additional diagnostic method in regard to the fetal screening process, mainly due to the fast development of fetal medicine and surgery. Compared…
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Skeletal Changes after Surgical Corrections in Skeletal Class III Patients

BACKGROUND. Skeletal class RIII (SRIII) is a dentofacial deformity, whose main characteristic is disharmony between upper and lower jaw with irregular position and/or size of upper and lower jaw in…
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The Role of Magnetic Resonance Imaging in Treating Patients with Phacomatosis – Case Report

Phacomatoses are a diverse group of genetic disorders that primarily affect the central nervous system, skin and other organs. Most commonly, dysfunction of the central nervous system is the prevailing…
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Malignant Spinal Cord Compression

Malignant spinal cord compression can lead to permanent neurological dysfunction and is therefore considered an oncological emergency. It is mostly caused by metastases to the spinal column, most frequently from…
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Vascular Anatomy – Venous Drainage to the Spine and the Spinal Cord

Venous drainage of the spine and the spinal cord is arranged like arteries in a reverse configuration. The vessels have very thin walls and are frequently without valves. The intraspinal…
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Simulation of Acute Left Ventricular Systolic and Diastolic Failure

Acute left ventricular systolic and acute left ventricular diastolic failures are very common conditions with a significant negative impact on the patient’s quality of life. Therefore, it is necessary that…
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Peritonsillar Abscess Complication: A Case Report

In the pre-antibiotic era, parapharyngeal infection was a frequent complication of tonsillitis. However, due to widespread use of antibiotics, its frequency has decreased and consequently the infection is quite uncommon…
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Crossed Aphasia in a Patient with Acute Ischemic Stroke? A Case Report

Crossed aphasia results from a lesion in a non-dominant, right cerebral hemisphere. This kind of neurological damage is rare and raises a number of issues in relation to the distribution…
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A Practical Approach to the Evaluation of Consciousness with the Glasgow Coma Scale

Glasgow coma scale was first defined in 1974. It was designed as a unified scoring system for assessing a patient’s conscious state. During the four decades of use, several versions…
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Treatment with Magnesium Sulphate for Cerebral Palsy Prevention in Preterm Birth: A Literature Review and Protocol Presentation

Cerebral palsy is a group of movement and posture disorders sometimes associated with other neurological deficits. It represents a significant decrease in the patients’ quality of life and a substantial…
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Diagnosis and Management of Diseases of Pulmonary Valve in Adult Patients

The pulmonary valve separates the right ventricle outflow tract from the pulmonary artery and prevents deoxygenated blood from the pulmonary artery to return into the right ventricle. The pulmonary valve…
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