Since 1962.

Research papers

Determination of estrogen receptors in small intestinal mucosa

Small intestinal mucosa of rats was tested for the presence of estrogen receptors. For determination of estrogen receptors  3H-estradiol 17-beta binding assay with or with our excess 1H-estradiol 17-beta was used. Three…
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Sensitivity of Neisseria gonorrhoeae to penicillin

Between September 1989 and October 1990, 25 gonococcal strains were isolated from 55 ureteral swabs of patients with clinical diagnosis of acute gonococcal infection. Their sensitivity to penicillin was determined…
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The correlation between the length of QTc interval, ventricular ectopic activity and ultrasonically determined impairment of the LV wall motion in acute myocardial infarction

The aim of the study was to determine: - whether in patients with acute myocardial infarction (AMI) the duration of the QTc interval correlates with the echocardiographically determined left ventricular…
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Some characteristics of patients with anorexia nervosa

Eight females with anorexia nervosa under treatment, and seven women with a past history of this disorder were evaluated by a directed interview. They were found to share several characteristic…
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Standardization of some cardiovascular tests in healthy children

Tests of cardiovascular reflexes and heart rate variability are reliable and noninvasive and therefore useful in children with suspected autonomic nerve dysfunction. The aim of this study was to calculate…
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Incidence of bacterial vaginosis and its relation to preterm delivery

Bacterial vaginosis is characterized by the presence of large amounts of anaerobic bac­teria, Gardnerella vaginalis and Mycoplasma hominis in the vagina, where they replace the nor­mally present lactobacilli. The condition…
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The role of microcystins in the development of parenchymal disorders

Microcystins damage liver tissue by disorganizing the cytoskeleton and inhibiting serine/threonine protein phosphatases. Liver cells shrink and blood penetrates the liver tissue. Internal bleeding may lead to haemorrhagic shock. Water…
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Experience of Reviewers of Student Research Works at the Ljubljana Faculty of Medicine

The purpose of student research is to acquire technical skills in the field of scientific research. Becoming familiar with research techniques has always attracted students at the Faculty of Medicine,…
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Splenectomy and the Immune Response

Backgrounds. Severe trauma of the spleen can be followed by excessive internal bleeding. The life of the injured person can be saved only with splenectomy. Removal of the spleen reduces…
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Acetylcholinesterase in Electrically Stimulated Denervated Muscle Extensor Digitorum Longus of the Rat

Background. The basis for the function of the nervous system is signalling among the nerve cells through the synapses. Normal signalling requires precise synthesis and localisation of synaptic structures within…
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Electrognathographic Assessment of the Area and Duration of the Chewing Cycle in Children during the Period of Deciduous Dentition and Early Mixed Dentition

BACKGROUNDS. Chewing is a cyclic mandibular movement on the functional teeth surfaces that prepares the bolus for swallowing with the help of the related nerves, muscles and soft tissues in…
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The Effect of Neurotrophin NT-3 on Functional Capabilities of Motoneurons in Cocultures with Human Muscle

Neurotrophins are a subgroup of growth factors acting within the nervous system. They are small proteins forming a family of several members. Among these, NT-3 is the most abun­dantly distributed…
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48-hour non-invasive ambulatory blood pressure monitoring in patients with end stage renal failure, treated by haemodialysis

The purpose of this prospective study was to determine the potential effects of various factors on blood pressure (BP) levels in 40 pa­tients treated by haemodialysis. A 48-hour non-in­vasive ambulatory…
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The influence of fluvoxamine and maprotiline on the release and kinetics of histamine in the rat in vivo

Antidepressants are known to influence the kinetics of histamine. The purpose of this study was twofold: to determine the influence of various doses of antidepressants fluvoxamine and mapro­tiline on induced…
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Results of the Reconstruction of the Foot with Musculo-Cutaneous Latissimus Dorsi Free Flap

The purpose of the study was to evaluate the results of operative reconstruction of the foot with a musculocutaneous latissimus dorsi free flap. At the Department of Plastic Surgery and…
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Induction of collateral sprouting of sensory axons in the rat

Collateral sprouting of axons in the pe­ripheral nervous system is a branching out­growth of new axon terminals from non-injured axons into adjacent denervated regions of tar­get tissue. The initiation of…
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The influence of alpha and beta fibrinogen genes’ polymorphisms on plasma fibrinogen level

Elevated plasma fibrinogen concen­tration is a risk factor for cardiovascular diseases. In addition to several factors such as advanced age, diabetes mellitus, cardiovascular disea­ses, elevated plasma cholesterol and glucose, and…
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Relationship between cytochrome P450 (CYP1A1) gene polymorphism and lung cancer susceptibility in Slovene population

Two polymorphic sites of the CYP1A1 gene, coding for cytochrome P4501A1 enzyme, have been discovered so far. One involves the 7th exon of the coding region; a nucleotide chan­ge leads…
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Cellular immune response to Borrelia burgdorferi infection in man

The purpose of this study was to de­termine the diagnostic value of the lymphocyte blast transformation test in Lyme disease. Our laboratory results were compared with the diag­noses established by…
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Examination of tick-borne encephalitis virus natural reservoirs in active and latent tick-borne encephalitis foci in Slovenia

Tick-borne encephalitis is the most important human central nervous system virus infection in Europe. The virus is maintained in nature by a cycle involving reservoirs (small mammals, deer) and vector…
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In vivo effects of actinoporins, isolated from Actinia equina

The mechanism of action of the actino­porins, substances from the sea anemone Actinia equina, is by cation selective pore formation in the cellular membranes that consequently cause cell lysis. The…
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Body movement patterns in normal and neurologically damaged newborns

Assessment of spontaneous body movements of newborns from video recordings is a diagnostic method that has not yet been introduced in Slovenia. Spontaneous move­ments of neurologically damaged newborns have been…
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Influence of hysteroscopic resection of septate uterus on reproductive prognosis and pregnancy

Septate uterus is one of the cogeni­tal abnormalities that causes the most problems. It is frequently the cause of spontaneous abor­tion, preterm labour, malpresentation or intrauter­ine growth retardation. Recently, hysteroscop­ic…
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Incidence of activated protein C resistance among patients with deep vein thrombosis

A group of 100 consecutive patients treated for deep vein thrombosis in the Trnovo Hospital of Internal Medicine from January 1992 to December 1994, was studied for the presence of…
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