Since 1962.

Research papers

Surgical treatment of Achilles tendon rupture

Currently, open surgical repair and per­cutaneous operation are the two most commonly used operative techniques for the repair of ruptured Achilles tendon. Open surgery is being increas­ingly replaced by the…
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The Effect of Tactile Stimulation on Physiological Parameters, Behavioural Response and Phase Adjustment of Rest-activity Rhythms in Newborn Infants

BACKGROUND. Infant tactile stimulation reduces distress behaviours, improves pulmonary function, weight gain per day, bone mineralization, developmentally appropriate functioning, enhances sleep organization and early attachment between infant and parents. We…
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Clinical, Immunological and Genetic Characteristics of Patients with Autoimmune Lymphoproliferative Syndrome in Slovenia

BACKGROUND. Autoimmune lymphoproliferative syndrome (ALPS) is a primary immuno­deficiency disorder characterized by immune dysregulation. ALPS is defined as chronic, nonmalignant lymphoproliferation in patients with double-negative T cell (DNT) expansion over…
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Survival of Patients with Ovarian Cancer

Data from 282 patients who were first treated for epithelial ovarian malignoma at the Institute of Oncology and Gynecological clinic in Ljubljana between 1990 and 1992 were analysed retrospectively. The…
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Comparison of Two Isotonic Beverages Drunk During a Long-distance Run

Drinking adequate amounts of fluid of appropriate composition during exercise can part­ly normalize abnormalities in homeostasis of body fluids and improve physical performance. The objective of this prospective comparative study…
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Disabilities and Rehabilitation Needs in Outpatients with Schizophrenia

The aim of this study was to identify the symptoms, disabilities and needs of schizophre­nic outpatients. Fifty schizophrenic outpatients (5% sample, 31 males and 19 females; mean age 43 years)…
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Evaluation of the Efficiency of Two Methods in Treating Acute Bronchiolitis in Small Children

Bronchiolitis is an acute respiratory disease of early childhood, mostly caused by res­piratory syncytial virus. A blind prospective study was undertaken to determine the effects of cor­ticosteroid therapy on the…
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Frequency of BRCA1 and BRCA2 Gene Mutations in Slovenian Male Breast Cancer Patients

Breast cancer is the most frequent cancer among women in Slovenia. Male breast cancer, how­ever, is a rare disease comprising less than 1% of breast cancer patients in Slovenia. The…
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Effect of Induced Hypothermia on Treatment of Patients after Cardiac Arrest

Cardiac arrest is the most common cause of sudden natural death. Ischemia during cardiac arrest and reperfusion damage after resuscitation are often the source of permanent neurological impairment in survivors.…
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Comorbidity of Depression and Sexual Dysfunction among Patients of Outpatient Clinic for Sexual Disorders’ Treatment

Sexual dysfunction and depression often occur together, however the causal relation is unclear and has not been studied enough. Sexual dysfunction secondary to depression has been well studied, but less…
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Effect of Atorvastatin on QTc Interval Duration in Patients with Heart Failure

Heart failure is related to QTc interval prolongation and changes in the QRS complex. Recently, elevated plasma levels of brain natriuretic peptide (proBNP) is also being recognized as an important…
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Electrocardiographic Changes in Children with Erythema Migrans

Lyme borreliosis is a worldwide tick-borne illness caused by the spirochete Borrelia burgdorferi sensu lato. The number of cases rises every year. The disease progresses with an unpredictable course and…
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Fluidity of Red Blood Cells’ Membranes in Cancer Patients − an Electronic Paramagnetic Resonance Study

Background: Hypocholesterolemia in cancer patients is a frequent and expected phenomenon. Higher fluidity of plasma membranes (as a result of lower concentration of cholesterol) is a characteristic of most cancer…
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Type and Activity of Inflammation in Obstructive Lung Diseases

Airway inflammation is fundamental to the persistence of asthma and chronic obstructive pulmonary disease. The hypothesis that induced sputum cell counts and mediators could help discriminate between asthma and chronic…
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Administration of Corticosteroids to Women during Pregnancy that Ends in Preterm Parturition

Preterm delivery is associated with neonatal mortality, severe neonatal morbidity with long-term consequences, and disturbances in neurologic development. However, when prevention of preterm delivery is impossible, preventative administration of corticosteroids…
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Optic Nerve Head Topography Analysis in Healthy Adults Using Heidelberg Retina Tomograph and Retinal Thickness Analyzer

Optic nerve head topography analysis using the Heidelberg retina tomograph I (HRT) and the Retinal thickness analyzer (RTA) is important in the early diagnosis and follow up of glau­coma. The…
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Psychosocial Risk Factors in Adolescents with Epilepsy

The aim of the study is to identify psychosocial risk factors among adolescents with epilepsy and compare them with those among healthy peers. We will also search for gender differences…
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Incidence of Depression in the Postpartum Period – Slovene Sample

Postpartum depression largely develops during the first six months following delivery. Its world-wide prevalence is between 3 and 33%, depending on the diagnostic methods and criteria. An attempt was made…
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Thirty-year Follow-up of Patients with Postpartum Psychiatric Disorders

The postpartum period is a time of rapid and fundamental biological, psychological and social changes, which can precipitate various psychiatric disorders in women. The aim of this study was to…
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Thickness of Carotid Arteries Intima and Media and Coronary Risk Factors

The coronary and carotid arterial beds are affected early in the process of atheroscle­rosis. Morphologic changes of arterial walls can be easily detected using B-mode ultrasound method. This technique enables…
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Lithium and peripheral nervous system function in manic-depressive patients

Influence of lithium on peripheral nervous function was evaluated by measuring 
of electrophysiological parameters in two 
groups of psychiatric patients (20 lithium treated
 and 20 affective-psychotic patients without the
 lithium…
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Release of tissue plasminogen activator during and after delivery

In late pregnancy and during delivery, blood fibrinolytic activity significantly changes. Those changes may be caused by changed levels of oxytocin and prolactin during 
and after delivery. Changes in oxytocin…
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Determination of the Most Favorable Regional Geometry in Hip Reconstruction after Femoral Neck Fracture

A mathematical model can be used to evaluate the biomechanical status of the hip after sur­gical intervention. By using such a model, it is possible to evaluate changes in the…
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Selection of Suitable Monoclonal Antibodies and Optimization of the Immunohistochemical Method for the Detection of Pathological Prion Protein in the Brains of Patients with Sporadic Creutzfeldt-Jakob Disease

Reliable diagnosis of prion diseases is based on a positive immunohistochemical reaction (IHR) using antibodies against prion protein (PrP). Unfortunately, this does not distinguish between cellular PrP (PrPC) and the…
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