Reliable diagnosis of prion diseases is based on a positive immunohistochemical reaction (IHR) using antibodies against prion protein (PrP). Unfortunately, this does not distinguish between cellular PrP (PrPC) and the…

Analysis of synovial fluid is of extreme importance for diagnosis and treatment 
of joint diseases. It is divided into general and 
special analysis. Analyses regarding colour, quantity, viscosity, transparency and…

Gallbladder perforation can appear as an acute perforation followed by biliary peritonitis, as subacute perforation with the formation of a pericholecystic abscess, or as a chronic con­dition leading to cholecysto-enteric…

The paper deals with vomiting and 
regurgitation in systematic and didactic way. In 
several section of the paper the following aspects of the disease are discussed: pathophysiology, causes and purposes…

By means of the matched pair method the difference in the frequency of the risk
 factor between a group of 46 patients with 
peripheral arterial occlusive disease and a group…

The annual and cumulative radiation exposure of the non-professional Slovene population is 21% greater than that world-wide, and so is the risk of stochastic effects. During a lifetime of 70…

This review presents the role of insulin in the regulation of blood pressure, lipid and 
protein metabolism, body weight and transmembraneous transport of sodium, magnesium and calcium. Insulin resistance may…

The demand for outpatient surgery and office-case anesthesia is increasing for medical, tech­nological and economic reasons. Ophtalmic day-case surgery and anesthesia have developed over the past ten years. Careful selection…

In this article the main features of
 microvascular angina pectoris are discussed in
 detail. The disease is characterized by angina
pectoris in the presence of arteriographically 
normal coronary arteries. This syndrome…

Diabetes mellitus can be explained
 pathophysiologically as a disorder impairing 
mechanisms responsible for normoglycemia. In
 the first part of the paper, entitled "Mechanisms
 underlying preservation of normoglycemia" these mechanisms are…

In developed countries, also in Slovenia − cerebrovascular diseases are the third most com­mon cause for death, and are on the top of the list of diseases that cause disablement. Epidemiological…

Calcium antagonists constitute a chemically 
and pharmacologically diverse group of drugs. Chemically, at least four major types of calcium antagonists can 
be distinguished; they include phenylalkylamines, dihydropyridines, benzothiazepines and piperazines.…

The cerebral cortex represents a relatively small part of the central nervous system. It con­tains a prodigious number of cells that lead our behaviour. In a general way, the central…

Two early phases of peritoneal cavity
 development are described: the primitive midline arrangement and shifts of viscera with their
mesenteries. The importance of these phases for the abdominal situs is presented.

The notochord and para-axial mesoderm induce the overlying ectoderm to differentiate into the neural plate. Formation of the neural tube begins in the fourth week, when the walls of the…

Psychosocial characteristics of 60 secondary school adolescent female suicide attempters 
were determined in the present study. We compared 
them with 60 secondary school females, representing a normal population. The data…

Exercise intolerance, a key symptom of chronic heart failure, has been linked to peripheral derangements, and marked endothelial dysfunction (i. e. the inability of endothelium to medi­ate a proper vasodilatatory…

Neisseria gonorrhoeae is a Gram negative diplococcus the cause of sexually transmitted dis­ease gonorrhea. It is transmitted through a promiscuous intercourse, from infected mother to the newborn and from one…

This paper deals with the issue of
 wound healing. The physiological aspect of this
 process is described. The authors introduce 
some simplifications and terms denoting combinations of several different wound…

Parkinson’s disease is a degenerative neurological disease progressing by affecting the abil­ities of communication (verbal, non-verbal, written). These disorders are present in a half to three-fourths of patients. Parkinson’s disease…

There were some studies reporting an increasing incidence of testicular cancer and geni­tourinary abnormalities such as cryptorchidism and hypospadias whereas human sperm quality is declining. Over the last decades, there…

In addition to the classical picture of endocapillary proliferative and exudative glomerulonephritis, patients with acute postinfectious glomerulonephritis may manifest a broad spectrum of various histomorphological and immunohistological changes which may reflect the stage of the…

Degeneration off the articular cartilage and osteoarthritis of the hip joint are most often idiopathic (primary osteoarthritis). In patients with known pathogenesis (secondary osteoarthrtis), the disease is most commonly due to mechanical bone deformation,…

Chronical periapical parodontitis is chronical inflamatory response of periapical parodon­tal tissues to bacterial infection. Patohistologically it represents nonspecifical chronical mononuclear inflamatory infiltration of fibrous tissue. Its pathogenesis depends on more…